• Source: Scopus
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20042020

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Personal profile

Research Biography

Dr Adeline Lau is a Research Fellow in Neurometabolic Disorders and joined the Flinders Health and Medical Research Institute (FHMRI) in January 2020. After completing her BBiotech (Hons) at Flinders University, she joined Associate Professor Kim Hemsley’s Childhood Dementia Research Group where she has been investigating novel therapeutic approaches for the treatment of early-onset neurodegenerative lysosomal storage disorders. As part of her PhD studies, Adeline was a visiting scientist in the laboratory of Dr Eric Kremer (Institut de Génétique Moléculaire de Montpellier, France), where she generated viral gene therapy vectors to examine the clinical efficacy of this approach using a mouse model of Sanfilippo syndrome using behavioural phenotyping, biochemical and histological techniques. Adeline’s research has evaluated therapies such as bone marrow transplantation, stem cell therapy, AAV and non-human adenoviral gene transfer and has more recently focussed on developing small molecule drugs such as pharmacological chaperones and heparan sulfate biosynthesis inhibitors.

Education/Academic qualification

PhD

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