Research Output per year
Research Output per year
Personal profile
Research Biography
Welcome to my home page. I am a Research Fellow in the Precision Medicine Group at the College of Medicine and Public Health, Flinders University.
My research interest is in using innovative modelling and simulation approaches to aid optimal drug development, precision drug use, and regulatory decisions. I use newly available clinical trial data to develop clinical prediction tools or applications that provide personalised likelihoods of expected therapeutic and adverse outcomes to contemporary rheumatoid arthritis and cancer medicines. Such tools allow informed treatment decisions to be made based on patient’s characteristics which may be predictive of efficacy or toxicity.
Our research group is always interested in identifying and working with PhD and Honours students, and have several projects available. Students would need to obtain a scholarship that will cover their own living expenses and tuition fees, but we are more than happy to support qualified students in applying for available funding. Please contact me if you are interested.
Education/Academic qualification
PhD, University of South Australia
15 Feb 2014 → 19 Jun 2017
Award Date: 19 Jun 2017
Master of Science, University of Iowa
10 Aug 2009 → 16 Dec 2011
Award Date: 16 Dec 2011
Bachelor of Science, University of Jordan
1 Sep 2004 → 15 Jun 2009
Award Date: 15 Jun 2009
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Research Output
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A safety, tolerability, and pharmacokinetic study of a novel simvastatin silica-lipid hybrid formulation in healthy male participants
Meola, T. R., Abuhelwa, A. Y., Joyce, P., Clifton, P. & Prestidge, C. A., 11 Sep 2020, In: Drug Delivery and Translational Research. 12 p.Research output: Contribution to journal › Article › peer-review
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Investigational IRAK-4 inhibitors for the treatment of rheumatoid arthritis
Wiese, M. D., Manning-Bennett, A. T. & Abuhelwa, A. Y., 3 May 2020, In: Expert Opinion On Investigational Drugs. 29, 5, p. 475-482 8 p.Research output: Contribution to journal › Review article › peer-review
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Population pharmacokinetic-pharmacodynamic modelling of liquid and controlled-release formulations of oxycodone in healthy volunteers
Ladebo, L., Foster, D. J. R., Abuhelwa, A. Y., Upton, R. N., Kongstad, K. T., Drewes, A. M., Christrup, L. L. & Olesen, A. E., Mar 2020, In: Basic and Clinical Pharmacology and Toxicology. 126, 3, p. 263-276 14 p.Research output: Contribution to journal › Article › peer-review
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Three-dimensional Printed 5-Fluorouracil Eluting Polyurethane Stents for the Treatment of Oesophageal Cancers
Fouladian, P., Kohlhagen, J., Arafat, M., Afinjuomo, F., Workman, N., Abuhelwa, A. Y., Song, Y., Garg, S. & Blencowe, A., 9 Dec 2020, In: Biomaterials Science. 8, 23, p. 6625-6636 12 p.Research output: Contribution to journal › Article › peer-review
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Mechanistic Assessment of the Effect of Omeprazole on the In Vivo Pharmacokinetics of Itraconazole in Healthy Volunteers
Abuhelwa, A. Y., Mudge, S., Upton, R. N. & Foster, D. J. R., 2019, In: European Journal of Drug Metabolism and Pharmacokinetics. 44, 2, p. 201-215 15 p.Research output: Contribution to journal › Article › peer-review