Dr Amanda Aloia

  • 516 Citations
  • 12 h-Index
20052019

Research output per year

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Personal profile

Research Biography

I completed my Honours degree in Nanotechnology (Biochemistry stream) at Flinders University while also working as a laboratory technician in the Department of Ophthalmology. My Honours and PhD research on the histamine and serotonin receptors was carried out in the laboratory of Prof. Edward J McMurchie at CSIRO in Adelaide and Parkville, in conjunction with Dr Ian Menz (Flinders). I also worked as research assistant in Prof. McMurchie's laboratory before beginning my PhD.

Following my PhD, I worked with Dr Reinhard Grisshammer at the National Institutes of Health (NIH) on the neurotensin-1 receptor, before changing my research focus to virology: a field I was especially interested in. With Dr Alan Rein at the National Cancer Institute (NIH), I developed assays for the detection of replication-competent retroviruses in gene-therapy products and contributed to the rapid investigations into a novel proposed human pathogen, Xenotropic Murine Leukemia Virus (XMRV).

I returned to Adelaide in 2012 to work on Hepatitis C Virus (HCV) with Assoc. Prof. Michael Beard, where I developed a novel HCV cell culture model and assessed the efficacy of direct-acting antivirals in collaboration with researchers from Merck Sharpe and Dohme. Returning to Flinders University in 2015, I worked with Dr Jill Carr on the inflammatory responses associated with Dengue Virus (DENV) infection.

I now manage the research facility, Cell Screen SA, within the Flinders Centre for Innovation in Cancer.

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Research Output

  • 516 Citations
  • 12 h-Index
  • 24 Article
  • 6 Paper
  • 1 Review article

In vitro and in vivo roles of sphingosine kinase 2 during dengue virus infection

Al-Shujairi, W. H., Clarke, J. N., Davies, L. T., Pitman, M. R., Calvert, J. K., Aloia, A. L., Pitson, S. M. & Carr, J. M., 1 Apr 2019, In : Journal of General Virology. 100, 4, p. 629-641 13 p.

Research output: Contribution to journalArticle

  • 2 Citations (Scopus)

    Automated Multiparameter Microscopy and Image Analysis: Next Generation Synovial Tissue Histology

    Murray-Brown, W., Weedon, H., Aloia, A., Lester, S., Proudman, S., Smith, M., Walker, J. & Wechalekar, M., 2018.

    Research output: Contribution to conferencePaper

    Dengue virus induces increased activity of the complement alternative pathway in infected cells

    Cabezas, S., Bracho Granado, G., Aloia, A., Adamson, P. J., Bonder, C. S., Smith, J. R., Gordon, D. L. & Carr, J. M., 2018, In : Journal of Virology. 92, 14, 20 p., e00633-18.

    Research output: Contribution to journalArticle

  • 7 Citations (Scopus)

    Genome-wide mutagenesis of dengue virus reveals plasticity of the NS1 protein and enables generation of infectious tagged reporter viruses.

    Eyre, N. S., Johnson, S. M., Eltahla, A. A., Aloi, M., Aloia, A. L., McDevitt, C. A., Bull, R. A. & Beard, M. R., 2017, In : Journal of Virology. 91, 23, 25 p., e01455-17.

    Research output: Contribution to journalArticle

  • 7 Citations (Scopus)

    Investigation of sphingosine kinase 1 in interferon responses during dengue virus infection

    Aloia, A. L., Calvert, J. K., Clarke, J. N., Davies, L. T., Helbig, K. J., Pitson, S. M. & Carr, J. M., 21 Jul 2017, In : Clinical & Translational Immunology. 6, 9 p., e151.

    Research output: Contribution to journalArticle

  • 4 Citations (Scopus)