Personal profile
Research Biography
Dr Andrew Hayles is a postdoctoral Research Associate in the Biomedical Nanoengineering Laboratory at the College of Medicine and Public Health, Flinders University. He has a keen research focus on antimicrobial materials, integrating microbiology, materials science, and biotechnology to combat microbial threats. He has significant translational experience, having worked on industrial-funded projects to commercialize a patented surface modification technique to produce antimicrobial nanostructures on titanium implants. As an early career researcher, Dr Hayles has been involved in multiple diverse projects, involving plasma-polymer surface modification, responsive nanoparticles and coatings, and biologically derived bioactive thin-films. Of note, he has spearheaded a novel field of research focused on exploiting the material-pathogen interface to promote the outcome of antimicrobial drugs against adherent pathogens. In this field, he has published multiple first-author and corresponding author publications in reputable journals including Acta Biomaterialia, npj Biofilms and Microbiomes and Advanced Biotechnology.
Dr Hayles has secured >$100,000 in competitive grant funding as lead investigator, including a Channel 7 Children’s Research Foundation Annual Grant (2025) and Flinders Foundation Health Seed Grant (2025).
Research Interests
- Biomaterials
- Antimicrobials
- Microbiology
- Antibiotic tolerance/resistance
- Surface engineering
- Nanoengineering
Education/Academic qualification
PhD, Hydrothermally Etched Titanium for the Mitigation of Implant Associated Infection, Flinders University
1 Feb 2021 → 28 Aug 2023
Award Date: 28 Sept 2023
Bachelor of Science, University of Adelaide
1 Jan 2015 → 31 Dec 2018
Award Date: 31 Dec 2018
Supervision
- Registered
Research Areas
- Biomedical engineering
- Nanotechnology
- Health sciences
- Medical biosciences
Keywords
- RS Pharmacy and materia medica
- RM Therapeutics. Pharmacology
- R Medicine (General)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Staphylococcus aureus surface attachment selectively influences tolerance against charged antibiotics
Hayles, A., Bright, R., Nguyen, N. H., Truong, V. K., Vongsvivut, J., Wood, J., Kidd, S. P. & Vasilev, K., Feb 2024, In: Acta Biomaterialia. 175, p. 369-381 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)78 Downloads (Pure) -
Vancomycin tolerance of adherent Staphylococcus aureus is impeded by nanospike-induced physiological changes
Hayles, A., Bright, R., Nguyen, N. H., Truong, V. K., Wood, J., Palms, D., Vongsvivut, J., Barker, D. & Vasilev, K., 29 Nov 2023, In: npj Biofilms and Microbiomes. 9, 1, 11 p., 90.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)74 Downloads (Pure) -
Gallium Liquid Metal: Nanotoolbox for Antimicrobial Applications
Truong, V. K., Hayles, A., Bright, R., Luu, T. Q., Dickey, M. D., Kalantar-Zadeh, K. & Vasilev, K., 8 Aug 2023, In: ACS nano. 17, 15, p. 14406-14423 18 p.Research output: Contribution to journal › Review article › peer-review
117 Citations (Scopus) -
Transforming Spirulina maxima Biomass into Ultrathin Bioactive Coatings Using an Atmospheric Plasma Jet: A New Approach to Healing of Infected Wounds
Pham, T., Nguyen, T. T., Nguyen, N. H., Hayles, A., Li, W., Pham, D. Q., Nguyen, C. K., Nguyen, T., Vongsvivut, J., Ninan, N., Sabri, Y., Zhang, W., Vasilev, K. & Truong, V. K., 26 Sept 2024, In: Small. 20, 39, 16 p., 2305469.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Citations (Scopus)236 Downloads (Pure) -
Surfaces Containing Sharp Nanostructures Enhance Antibiotic Efficacy
Bright, R., Hayles, A., Wood, J., Palms, D., Brown, T., Barker, D. & Vasilev, K., 24 Aug 2022, In: Nano Letters. 22, 16, p. 6724–6731 8 p.Research output: Contribution to journal › Article › peer-review
36 Citations (Scopus)
Projects
- 1 Active
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Elucidating the Role of Biomaterial Surface Charge in Antibiotic Tolerance of Adhered Pathogens
Hayles, A. (Chief Investigator (Project Lead)), Jaarsma, R. (Chief Investigator), Vasilev, K. (Associate Investigator) & Bright, R. (Associate Investigator)
1/03/25 → 28/02/27
Project: Research