Research output per year
Research output per year
Personal profile
Research Biography
Arduino trained in Clinical Pharmacology, Cardiology and Internal Medicine in Milan, Boston and London. In 2003 he was awarded a PhD at King's College London and was appointed as Senior Lecturer in the Department of Clinical Pharmacology at Flinders University. He was promoted to Associate Professor in 2007 before taking up the Chair of Medicine of Old Age at the University of Aberdeen in 2010. In 2013 he returned to Flinders University as Professor of Clinical Pharmacology and Senior Consultant in Clinical Pharmacology and Internal Medicine.
Research Interests
- Chemistry of dimethylarginine dimethylaminohydrolase 1 (DDAH1)
- Effect of DDAH1 inhibition in experimental models of cancer and fibrosis
- Arginine metabolomics and age-associated disease states
- Pharmacoepidemiology and drug safety in old age
- Identification and assessment of patient-centred outcomes in old age
- Autoimmune disease states as a model of premature vascular ageing and atherosclerosis
- Repurposing of anti-inflammatory drugs for cardiovascular risk management
Supervised Students Successes
- Apr 2018 Leena Baghdadi - Best PhD Thesis
- May 2017 Leena Baghdadi - Best research manuscript
Completed Supervisions
Principal Supervisions:
- Pharmacology (2)
- Design of novel DDAH inhibitors (Univ of Aberdeen) (1)
- Methotrexate and markers of cardiovascular risk in rheumatoid arthritis (Univ of Aberdeen) (1)
Associate Supervisions:
- Pharmacology (3)
Supervision
- Registered
Research Areas
- Medical biosciences
Supervisory Interests
- Clinical pharmacology
- Cardiovascular and internal medicine
- Pharmacological interventions on cardiovascular function
- Structure/function of vascular beds
- Hypertension/cardiology
- Clinical biochemistry
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger -
SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 5 Gender Equality -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 16 Peace, Justice and Strong Institutions
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A RETROSPECTIVE ANALYSIS OF RISK FACTORS FOR RESPIRATORY FAILURE IN SILICOSIS PATIENTS EXPOSED TO GRANITE DUST
Zinellu, E., Piras, B., Di Lorenzo, B., Albrahimi, E., Zoroddu, S., Pau, M. C., Scala, C., Fois, S. S., Mangoni, A. A., Carru, C., Fois, A. G., Zinellu, A. & Pirina, P., 6 Mar 2026, (E-pub ahead of print) In: Journal of Occupational and Environmental Medicine. 22 p.Research output: Contribution to journal › Article › peer-review
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A systematic review and meta-analysis of the systemic immune-inflammation index (SII) in rheumatic diseases
Mangoni, A. A. & Zinellu, A., 13 Jul 2026, In: Frontiers in Immunology. 17, 12 p., 1896434.Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Comparative Evaluation of Machine Learning Models Using Structured and Unstructured Clinical Data for Predicting Unplanned General Medicine Readmissions in a Tertiary Hospital in Australia
Sharma, Y., Thompson, C., Mangoni, A., Horwood, C. & Woodman, R., Mar 2026, In: Computers. 15, 3, 23 p., 138.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)6 Downloads (Pure) -
Current Reviews in Clinical and Experimental Pharmacology (CRCEP)-Preface-2026
Mangoni, A. A., 2026, In: Current Reviews in Clinical and Experimental Pharmacology. 21, 1, p. iv 1 p.Research output: Contribution to journal › Editorial
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DDAH1 and DDAH2 drive vasculogenic mimicry and more aggressive phenotypes in triple negative breast cancer cells
Meyers, J., Weerakoon, L., Ragavan, V., Jarzebska, N., Rodionov, R. N., Mangoni, A. A., Hulin, J. A. & Tommasi, S., Aug 2026, In: Biomedicine and Pharmacotherapy. 201, 8 p., 119759.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure)
Projects
- 5 Active
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Effects of fucoidans in triple negative breast cancer
Mangoni, A. (Chief Investigator (Project Lead)), Meyers, J. (Chief Investigator) & Wimmer, B. C. (Chief Investigator)
17/04/26 → 17/10/29
Project: Research
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FF25: Pilot Randomised Controlled Trial of Vitamin C Supplementation in Hospitalised Patients with Community-Acquired Pneumonia: Effect on Inflammatory Biomarkers
Sharma, Y. (Chief Investigator (Project Lead)), Woodman, R. (Chief Investigator), Thompson, C. (Chief Investigator), Ng, H. S. (Chief Investigator), Mangoni, A. (Associate Investigator), SUMANDASA, S. (Associate Investigator), Arthur, M. (Associate Investigator), Tommasi, S. (Associate Investigator) & Whiteway, L. (Associate Investigator)
2/03/26 → 29/02/28
Project: Research
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FF25: Investigation of the cardio-protective effects of methotrexate: a new approach to treatment of rheumatoid arthritis and its cardiovascular complications
Tommasi, S. (Chief Investigator (Project Lead)), Hulin, J.-A. (Chief Investigator), Woodman, R. (Associate Investigator), Shanahan, M. (Associate Investigator), Brown, S. (Associate Investigator) & Mangoni, A. (Associate Investigator)
2/03/26 → 29/02/28
Project: Research
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Investigation of the protective effects of fucoidan extracts on endothelial glycocalyx in vitro
Mangoni, A. (Chief Investigator (Project Lead)), Meyers, J. (Chief Investigator), Dwan, C. (Chief Investigator) & Wimmer, B. C. (Chief Investigator)
1/04/25 → 31/01/27
Project: Research
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Developing an AI Precision-medicine clinical decision support tool for older patients
Woodman, R. (Chief Investigator (Project Lead)), Mangoni, A. (Chief Investigator), Shi, J. Q. (Chief Investigator), Ng, H. S. (Chief Investigator), Liu, L. (Associate Investigator), Hopkins, A. (Associate Investigator), Thompson, C. (Associate Investigator) & Russell, P. (Associate Investigator)
1/03/25 → 28/02/27
Project: Research
Activities
- 1 Oral presentation
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Co-morbidities in breast cancer survivors: Prevalence and management
Koczwara, B. (Speaker), Mangoni, A. (Speaker), Meng, R. (Speaker), Spencer, D. (Speaker), Battersby, M. (Speaker) & Lawn, S. (Speaker)
8 Feb 2018 → 9 Feb 2018Activity: Talk or presentation types › Oral presentation