Dr Binoy Appukuttan

  • 2045 Citations
  • 19 h-Index
1994 …2020

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Article
2020

Lamb as a potential source of Toxoplasma gondii infection for Australians

Dawson, A. C., Ashander, L. M., Appukuttan, B., Woodman, R. J., Dubey, J. P., Whiley, H. & Smith, J. R., 1 Feb 2020, In : Australian and New Zealand Journal of Public Health. 44, 1, p. 49-52 4 p.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
26 Downloads (Pure)
2019

Expression of Long Non-Coding RNAs by Human Retinal Müller Glial Cells Infected with Clonal and Exotic Virulent Toxoplasma gondii

Rochet, E., Appukuttan, B., Ma, Y., Ashander, L. & Smith, J., Sep 2019, In : Non-coding RNA. 5, 4, 15 p., 48.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
3 Downloads (Pure)

Expression of microRNA in human retinal pigment epithelial cells following infection with Zaire ebolavirus

Oliver, G., Valinezhad Orang, A., Appukuttan, B., Marri, S., Michael, M., Marsh, G. & Smith, J., 1 Oct 2019, In : BMC Research Notes. 12, 639, 7 p., 639.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
3 Downloads (Pure)

Immunological Molecular Responses of Human Retinal Pigment Epithelial Cells to Infection With Toxoplasma gondii

Lie, S., Rochet, E., Segerdell, E., Ma, Y., Ashander, L. M., Shadforth, A. M. A., Blenkinsop, T. A., Michael, M. Z., Appukuttan, B., Wilmot, B. & Smith, J. R., 1 May 2019, In : Frontiers in Immunology. 10, 18 p.

Research output: Contribution to journalArticle

Open Access
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6 Citations (Scopus)

Neutrophil Activities in Human Ocular Toxoplasmosis: An In Vitro Study With Human Cells

Ashander, L. M., Lie, S., Ma, Y., Rochet, E., Washington, J. M., Furtado, J. M., Appukuttan, B. & Smith, J. R., Nov 2019, In : Investigative Ophthalmology & Visual Science. 60, 14, p. 4652-4660 9 p.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
7 Downloads (Pure)
2018
3 Citations (Scopus)

Effect of NADPH oxidase 1 and 4 blockade in activated human retinal endothelial cells

Appukuttan, B., Ma, Y., Stempel, A., Ashander, L., Deliyanti, D., Wilkinson-Berka, J. & Smith, J., Aug 2018, In : Clinical and Experimental Ophthalmology. 46, 6, p. 652-660 9 p.

Research output: Contribution to journalArticle

Open Access
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10 Citations (Scopus)
5 Downloads (Pure)

Emerging diagnostic tests for vitreoretinal lymphoma: a review

Dawson, A., Williams, K., Appukuttan, B. & Smith, J., 13 Apr 2018, In : Clinical and Experimental Ophthalmology. 46, 8, p. 945-954 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

ICAM-1-related long non-coding RNA: promoter analysis and expression in human retinal endothelial cells

Lumsden, A. L., Ma, Y., Ashander, L. M., Stempel, A. J., Keating, D. J., Smith, J. R. & Appukuttan, B., 2018, In : BMC Research Notes. 11, 1, 8 p., 285.

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)
2017

Molecular responses of human retinal cells to infection with Dengue Virus

Carr, J., Ashander, L., Calvert, J., Ma, Y., Aloia, A., Bracho, G., Chee, S-P., Appukuttan, B. & Smith, J., 2017, In : Mediators of Inflammation. 2017, 16 p., 3164375.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
1 Downloads (Pure)

Molecular Signals Involved in Human B Cell Migration into the Retina: In Vitro Investigation of ICAM-1, VCAM-1, and CXCL13

Bharadwaj, A., Stempel, A., Olivas, A., Franzese, S., Ashander, L., Ma, Y., Lie, S., Appukuttan, B. & Smith, J., 2017, In : Ocular Immunology and Inflammation. 25, 6, p. 811-819 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Retinal Pigment Epithelial Cells are a Potential Reservoir for Ebola Virus in the Human Eye

Smith, J., Todd, S., Ashander, L., Charitou, T., Ma, Y., Yeh, S., Crozier, I., Michael, M., Appukuttan, B., Williams, K., Lynn, D. & Marsh, G., 2017, In : Translational Vision Science & Technology. 6, 4, 15 p., 12.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2016

Targeting Endothelial Adhesion Molecule Transcription for Treatment of Inflammatory Disease: A Proof-of-Concept Study

Ashander, L., Appukuttan, B., Ma, Y., Gardner-Stephen, D. & Smith, J., 2016, In : Mediators of Inflammation. 2016, 9 p., 7945848.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2015

Genome-wide association study for sight-threatening diabetic retinopathy reveals association with genetic variation near the GRB2 gene

Burdon, K., Fogarty, R., Shen, W., Abhary, S., Kaidonis, G., Appukuttan, B., Hewitt, A., Sharma, S., Daniell, M., Essex, R., Chang, J., Klebe, S., Lake, S., Pal, B., Jenkins, A., Govindarjan, G., Sundaresan, P., Lamoureux, E., Ramasamy, K., Pefkianaki, M. & 5 others, Hykin, P., Petrovsky, N., Brown, M., Gillies, M. & Craig, J., 2015, In : Diabetologia. 58, 10, p. 2288-2297 10 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Ubiquitin Carboxyl-Terminal Esterase L1 Promotes Proliferation of Human Choroidal and Retinal Endothelial Cells

Pan, Y., Appukuttan, B., Mohs, K., Ashander, L. & Smith, J., 2015, In : Asia-Pacific Journal of Ophthalmology. 4, 1, p. 51-55 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2014

Genetic variation near GRB2 and KCNB2 identified by a genome-wide association study are reproducibly associated with Diabetic Retinopathy

Kaidonis, G., Craig, J., Fogarty, R., Gillies, M., Shen, W., Sharma, S., Appukuttan, B., Pal, B., Sundaresan, P. & Burdon, K., Apr 2014, In : Investigative Ophthalmology and Visual Science. 55, 13, p. 2237-2237 1 p., 2267560.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Recombinant Filaggrin Is Internalized and Processed to Correct Filaggrin Deficiency

Stout, T., McFarland, T., Mitchell, J., Appukuttan, B. & Stout, J., 2014, In : Journal of Investigative Dermatology. 134, 2, p. 423-429 7 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Simultaneous Visualization and Cell-Specific Confirmation of RNA and Protein in the Mouse Retina

Stempel, A., Morgans, C., Stout, J. & Appukuttan, B., 2014, In : Molecular Vision. 20, p. 1366-1373 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Suppression of Neovascularization of Donor Corneas by Transduction with Equine Infectious Anemia Virus-Based Lentiviral Vectors Expressing Endostatin and Angiostatin

Parker, M., Bellec, J., McFarland, T., Scripps, V., Appukuttan, B., Hartzell, M., Yeager, A., Hady, T., Mitrophanous, K., Stout, T. & Ellis, S., 2014, In : HUMAN GENE THERAPY. 25, 5, p. 408-418 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2013

Role of the retinal vascular endothelial cell in ocular disease

Bharadwaj, A., Appukuttan, B., Wilmarth, P., Pan, Y., Stempel, A., Chipps, T., Benedetti, E., Zamora, D., Choi, D., David, L. & Smith, J., Jan 2013, In : Progress in Retinal and Eye Research. 32, 1, p. 102-180 79 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Toxoplasma gondii Migration within and Infection of Human Retina

Furtado, J., Ashander, L., Mohs, K., Chipps, T., Appukuttan, B. & Smith, J., 21 Feb 2013, In : PLoS One. 8, 2, p. e54358 6 p., e54358.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2012

Expression and regulation of activated leukocyte cell adhesion molecule in human retinal vascular endothelial cells

Smith, J., Chipps, T., Ilias, H., Pan, Y. & Appukuttan, B., Nov 2012, In : Experimental Eye Research. 104, p. 89-93 5 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Imaging Retinal Vascular Changes in the Mouse Model of Oxygen-Induced Retinopathy

Furtado, J., Davies, M., Choi, D., Lauer, A., Appukuttan, B., Bailey, S., Rahman, H., Payne, J., Stempel, A., Mohs, K., Powers, M., Yeh, S. & Smith, J., 2012, In : Translational Vision Science & Technology. 1, 2, p. Article 5 9 p.

Research output: Contribution to journalArticle

The related transcriptional enhancer factor-1 Isoform, TEAD4216, can repress vascular endothelial growth factor expression in mammalian cells

Appukuttan, B., McFarland, T., Stempel, A., Kassem, J., Hartzell, M., Zhang, Y., Bond, D., West, K., Wilson, R., Stout, A., Pan, Y., Ilias, H., Robertson, K., Klein, M., Wilson, D., Smith, J. & Stout, J., 22 Jun 2012, In : PLoS One. 7, 6, p. e31260 12 p., e31260.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2010

Non-invasive stem cell therapy in a rat model for retinal degeneration and vascular pathology

Wang, S., Lu, B., Girman, S., Duan, J., McFarland, T., Zhang, Q., Grompe, M., Adamus, G., Appukuttan, B. & Lund, R., 15 Feb 2010, In : PLoS One. 5, 2, p. e9200 9 p., e9200.

Research output: Contribution to journalArticle

111 Citations (Scopus)
2009

Subretinal transplantation of forebrain progenitor cells in nonhuman primates: Survival and intact retinal function

Francis, P., Wang, S., Zhang, Y., Brown, A., Hwang, T., McFarland, T., Jeffrey, B., Lu, B., Wright, L., Appukuttan, B., Wilson, D., Stout, J., Neuringer, M., Gamm, D. & Lund, R., 2009, In : Investigative Ophthalmology and Visual Science. 50, 7, p. 3425-3431 7 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2008

Human CHN1 mutations hyperactivate alpha2-chimaerin and cause Duane's retraction syndrome

Miyake, N., Chilton, J., Psatha, M., Cheng, L., Andrews, C., Chan, W-M., Law, K., Crosier, M., Lindsay, S., Cheung, M., Allen, J., Gutowski, N., Ellard, S., Young, E., Iannaccone, A., Appukuttan, B., Stout, J., Christiansen, S., Ciccarelli, M., Baldi, A. & 7 others, Campioni, M., Zenteno, J., Davenport, D., Mariani, L., Sahin, M., Guthrie, S. & Engle, E., 2008, In : Science. 321, 5890, p. 839-843 5 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)

Natural history and histology in a rat model of laser-induced photothrombotic retinal vein occlusion

Zhang, Y., Fortune, B., Atchaneeyasakul, L-O., McFarland, T., Mose, K., Wallace, P., Main, J., Wilson, D., Appukuttan, B. & Stout, J., 2008, In : Current Eye Research. 33, 4, p. 365-376 12 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Prediction of cis-regulatory elements controlling genes differentially expressed by retinal and choroidal vascular endothelial cells

Choi, D., Appukuttan, B., Binek, S., Planck, S., Stout, J., Rosenbaum, J. & Smith, J., 2008, In : Journal of Ocular Biology, Diseases and Informatics. 1, 1, p. 37-45 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Rhesus monkeys and humans share common susceptibility genes for age-related macular disease

Francis, P., Appukuttan, B., Simmons, E., Landauer, N., Stoddard, J., Hamon, S., Ott, J., Ferguson, B., Klein, M., Stout, J. & Neuringer, M., 2008, In : Human Molecular Genetics. 17, 17, p. 2673-2680 8 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

Kleinman, M., Yamada, K., Takeda, A., Chandrasekaran, V., Nozaki, M., Baffi, J., Albuquerque, R., Yamasaki, S., Itaya, M., Pan, Y., Appukuttan, B., Gibbs, D., Yang, Z., Kariko, K., Ambati, B., Wilgus, T., DiPietro, L., Sakurai, E., Zhang, K., Smith, J. & 2 others, Taylor, E. & Ambati, J., 2008, In : Nature. 452, 7187, p. 591-597 7 p.

Research output: Contribution to journalArticle

733 Citations (Scopus)
2007

Identification of novel alternatively spliced isoforms of RTEF-1 within human ocular vascular endothelial cells and murine retina.

Appukuttan, B., McFarland, T., Davies, M., Atchaneeyasakul, L-O., Zhang, Y., Babra, B., Pan, Y., Rosenbaum, J., Acott, T., Powers, M. & Stout, J., 2007, In : Investigative Ophthalmology & Visual Science. 48, 8, p. 3775-3782 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Internal en bloc resection and genetic analysis of retinal capillary hemangioblastoma.

Schlesinger, T., Appukuttan, B., Hwang, T., Atchaneeyasakul, L-O., Chan, C., Zhuang, Z., Stout, J. & Wilson, D., 2007, In : Archives of Ophthalmology. 125, 9, p. 1189-1193 5 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Suppression subtractive hybridization identifies novel transcripts in regenerating Hydra littoralis.

Stout, T., McFarland, T. & Appukuttan, B., 2007, In : JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY. 40, 2, p. 286-289 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2006

A novel H572R mutation in the transforming growth factor-beta-induced gene in a Thai family with lattice corneal dystrophy type I.

Atchaneeyasakul, L-O., Appukuttan, B., Pingsuthiwong, S., Yenchitsomanus, P., Trinavarat, A., Srisawat, C., McFarland, T., Stout, J., Wichyanuwat, P. & Thongnoppakhun, W., 2006, In : JAPANESE JOURNAL OF OPHTHALMOLOGY. 50, 5, p. 403-408 6 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Evaluation of a Novel Short Polyadenylation Signal as an Alternative to the SV40 Polyadenylation Signal.

McFarland, T., Zhang, Y., Atchaneeyasakul, L-O., Francis, P., Stout, J. & Appukuttan, B., 2006, In : Plasmid. 56, 1, p. 62-67 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2005

Activation of the Mitochondrial Apoptotic Pathway in A Rat Model of Central Retinal Artery Occlusion.

Zhang, Y., Cho, C-H., Atchaneeyasakul, L-O., McFarland, T., Appukuttan, B. & Stout, J., 2005, In : Investigative Ophthalmology & Visual Science. 46, 6, p. 2133-2139 7 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)
2004

An Unusual Clinical Phenotype of Avellino Corneal Dystrophy Associated with an Arg124His beta iG-H3 Mutation in an African-American Woman.

Meallet, M., Affeldt, J., McFarland, T., Appukuttan, B., Read, R., Stout, J. & Rao, N., 2004, In : American Journal of Ophthalmology. 137, 4, p. 765-767 3 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Gene Therapy for Proliferative Ocular Disease.

McFarland, T., Zhang, Y., Appukuttan, B. & Stout, J., 2004, In : Expert Opinion on Biological Therapy. 4, 7, p. 1053-1058 6 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2003

Corneal transduction to inhibit angiogenesis and graft failure

Murthy, R., McFarland, T., Yoken, J., Chen, S., Barone, C., Burke, D., Zhang, Y., Appukuttan, B. & Stout, J., 2003, In : Investigative Ophthalmology & Visual Science. 44, 5, p. 1837-1842 6 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)
2002

Electronegative Electroretinogram in Mucolipidosis IV

Pradhan, S., Atchaneeyasakul, L-O., Appukuttan, B., Mixon, R., McFarland, T., Billingslea, A., Wilson, D., Stout, J. & Weleber, R., 2002, In : Archives of Ophthalmology. 120, 1, p. 45-50 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2000

A novel mutation in the Norrie disease gene.

Ott, S., Patel, R., Appukuttan, B., Wang, X. & Stout, J., 2000, In : Journal of AAPOS. 4, 2, p. 125-126 2 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Clinical Phenotype Associated With the Arg141His Mutation in the X-linked Retinoschisis Gene.

Park, J-H., Ott, S., Wang, X., Appukuttan, B., Patel, R., Van Boemel, G. B. & Stout, J., 2000, In : Archives of Ophthalmology. 118, 1, p. 127-129 3 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

DNA-based diagnosis of the von Hippel-Lindau syndrome.

Patel, R., Appukuttan, B., Ott, S., Wang, X. & Stout, J., 2000, In : American Journal of Ophthalmology. 129, 2, p. 258-260 3 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Efficient and Sustained Transgene Expression in Human Corneal Cells Mediated by a Lentiviral Vector.

Wang, X., Appukuttan, B., Ott, S., Patel, R., Irvine, J., Song, J., Park, J-H., Smith, R. & Stout, J., 2000, In : Gene Therapy. 7, 3, p. 196-200 5 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Expression of a recombinant human RGR opsin in Lentivirus-transduced cultured cells.

Yang, M., Wang, X., Stout, J., Chen, P., Hjelmeland, L., Appukuttan, B. & Fong, H., 2000, In : Molecular Vision. 6, 32, p. 237-242 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Heterozygous loss of Six5 in mice is sufficient to cause ocular cataracts.

Sarkar, P., Appukuttan, B., Han, J., Ito, Y., Ai, C., Tsai, W., Chai, Y., Stout, J. & Reddy, S., 2000, In : Nature Genetics. 25, 1, p. 110-114 5 p.

Research output: Contribution to journalArticle

142 Citations (Scopus)

Isolation and characterization of the human homeobox gene HOX D1.

Appukuttan, B., Sood, R., Ott, S., Makalowska, I., Patel, R., Wang, X., Robbins, C., Brownstein, M. & Stout, J., 2000, In : Molecular Biology Reports. 27, 4, p. 195-201 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
1999

Exclusion of candidate genetic loci for Duane retraction syndrome.

Ott, S., Borchert, M., Chung, M., Appukuttan, B., Wang, X., Weinberg, K. & Stout, J., 1999, In : American Journal of Ophthalmology. 127, 3, p. 358-360 3 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)