Research output per year
Research output per year
Personal profile
Education/Academic qualification
Bachelor of Science (Honours), Honours Degree of Bachelor of Science with First Class Honours: Molecular and Cellular Biology, University of Adelaide
1 Feb 2017 → 8 Jan 2018
Award Date: 8 Jan 2018
Bachelor of Science, Bachelor of Science (Advanced): Biochemistry and Chemistry, University of Adelaide
1 Mar 2014 → 31 Dec 2016
Award Date: 31 Dec 2016
PhD, Precision Medicine Approaches for JAK2- Rearranged Acute Lymphoblastic Leukaemia: The Efficacy of Targeted Therapies and Molecular Mechanisms of Drug Resistance, University of Adelaide
14 Feb 2018 → …
External positions
Junior Researcher, SAHMRI
6 Dec 2021 → 26 Jun 2022
Demonstrator, University of Adelaide
1 Mar 2021 → 22 Jul 2022
Supervision
- Registered
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Case Report: Rare IKZF1 Gene Fusions Identified in Neonate with Congenital KMT2A-Rearranged Acute Lymphoblastic Leukemia
Eadie, L. N., Rehn, J. A., Breen, J., Osborn, M. P., Jessop, S., Downes, C. E. J., Heatley, S. L., McClure, B. J., Yeung, D. T., Revesz, T., Saxon, B. & White, D. L., Feb 2023, In: Genes. 14, 2, 11 p., 264.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)34 Downloads (Pure) -
Identification of a novel GOLGA4–JAK2 fusion gene in B-cell acute lymphoblastic leukaemia
Downes, C. E. J., Rehn, J., Heatley, S. L., Yeung, D., McClure, B. J. & White, D. L., Feb 2022, In: British Journal of Haematology. 196, 3, p. 700-705 6 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
JAK2 Alterations in Acute Lymphoblastic Leukemia: Molecular Insights for Superior Precision Medicine Strategies
Downes, C. E. J., McClure, B. J., McDougal, D. P., Heatley, S. L., Bruning, J. B., Thomas, D., Yeung, D. T. & White, D. L., 12 Jul 2022, In: Frontiers in Cell and Developmental Biology. 10, 34 p., 942053.Research output: Contribution to journal › Review article › peer-review
Open AccessFile16 Citations (Scopus)93 Downloads (Pure) -
Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia
Downes, C. E. J., McClure, B. J., Bruning, J. B., Page, E., Breen, J., Rehn, J., Yeung, D. T. & White, D. L., 10 Aug 2021, In: npj Precision Oncology. 5, 13 p., 75.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)44 Downloads (Pure) -
Acquired mutations within the JAK2 kinase domain confer resistance to JAK inhibitors in in vitro models of acute lymphoblastic leukaemia
Downes, C., McClure, B., Bruning, J., Breen, J., Rehn, J., Yeung, D. & White, D. L., 20 Sept 2021, p. 58. 1 p.Research output: Contribution to conference › Abstract
Prizes
Activities
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AusBiotech (External organisation)
Charlotte EJ Downes (Member)
Sept 2022 → Aug 2023Activity: Membership types › Membership of network
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Cancer Letters (Journal)
Charlotte EJ Downes (Reviewer)
Feb 2022Activity: Publication peer-review and editorial work types › Publication Peer-review
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Precision medicine approaches and drug resistance in JAK2-rearranged acute lymphoblastic leukaemia
Charlotte Downes (Speaker)
2021Activity: Talk or presentation types › Oral presentation
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Australian and New Zealand Children's Haematology/Oncology Group (ANZCHOG) Annual Scientific Meeting 2021
Charlotte Downes (Participant)
30 Jun 2021Activity: Participating in or organising an event types › Participating in a conference, workshop, ...
File -
Acquired mutations within the JAK2 kinase domain confer resistance to JAK inhibitors in in vitro models of acute lymphoblastic leukaemia
Charlotte Downes (Speaker)
Sept 2021Activity: Talk or presentation types › Oral presentation