Personal profile
Research Biography
Professor Christopher Franco's research career combines both the industrial and academic spheres. For 10 years he led a successful drug discovery and development group in an International biopharmaceutical company and holds patents for 11 compound families. In 1993, he joined the School of Medicine, as a founding academic in the Biotechnology Program. Now Head, Medical Biotechnology, he manages the Biotechnology teaching and research programs in the College of Medicine and Public Health. He is an accomplished Research supervisor, successfully completing over 35 PhD and 55 Honours/Masters students.
He is Australia's leading actinobacteriologist and continues to discover novel actinobacteria and new bioactives from algae, plant cell culture, mammalian cells and marine organisms. He pioneered the isolation and application of actinobacterial endopytes for sustainable crop production and was awarded the prestigious Australian Museum Eureka Prize (2004). He headed the GRDC's multi-institutional Beneficial Microbes Project which resulted in microbial inoculants which are in commerciial development.
He is a founding member of the Flinders Centre for Marine Bioproducts Development. He has extensive international experience, working in the UK, Germany, India, Indonesia, Singapore and China and was International Dean, Faculty of Medicine, Nursing & Health Sciences and the School of Medicine. He collaborates with researchers in Asia, Europe and N.America.
Research Interests
Details of Research projects:
Actinomycetes and Pharmaceutical Biotechnology
- Strategies for the isolation of novel actinobacteria
- Discovery of novel microbial metabolites
- Actinomycete ecology and characterisation
- Molecular biology techniques in biodiversity
- Actinobacterial endophytes- pharmaceutical and agricultural applications
Bioprocessing
- Fermentation technology of microbial and plant cells
- Expression and manipulation of secondary metabolism
- Purification and characterisation of actinobacterial compounds
- Bioprocessing for functional foods and cosmeceuticals
- Biofuels and renewable energy
Marine Biotechnology
- Bioactives from seaweed, sponge and sea cucumbers
- Prebiotic evaluation of seaweed and seaweed components
- Value addition to fish processing co-products
- Sponge-bacterial interactions
External Research Collaborations
- Chris Dunlap (USDA- NRRL) on NGS of wheat growing ecosystems
- Anil Sharma, Pantnagar, and Gupta Vadakattu, CSIRO, Adelaide . Australia india Strategic Research Fund on wheat microbiome to counter drought stress.
- Yonghua Zhu, Hunan University. GM Rice -environmental impact
- Steve Barnett, Ross Ballard (SARDI) and Lambert Brau (Murdoch Univ). GRDC Beneficial Microbes Programs 1 and 2.
- Qingdao Great Gather Ocean Group, Qingdao, on new products from Sea weed.
- Ross Ballard & Dr Liz Drew (SARDI), Interactions of Beneficial Microbes
- Calum Wilson & Robert Teeg (Univ. Tasmania). HAL: Application of Actinobacterial endophytes for potato cultivation and disease control.
- Eileen Scott & Amanda Able (Univ Adelaide) on Control of Phytophtora. Co-supervision of PhD candidate.
- Gupta Vadakattu, CSIRO Ecosystems, Adelaide, Co-supervision of Research Higher degree students
- Ern Lacey, MST Sydney, on Screening and production of new actinoband molecular acterial metabolites.
- Margaret Roper, CSIRO Plant Industries, Perth, on Plant-associated microorganisms for improved grain yield. Co-Investigator on GRDC grant.
- Rose Loria, Dept Plant Pathology, Cornell University, on Molecular interactions of actinomycete endophytes.
- CRC for Seafood, with Simplot Australia and Tasmanian Seafoods on Seafood co-product utilisation and sea cuucmber
Supervised Students Successes
- Aug 2013 Qi Yang - People's choice award -3MT competition
Completed Supervisions
- Actinobacterial endophyte function and ecology (10)
- Optimising Plant Cell culture (6)
- Actinobacterial discovery, taxonomy and application (5)
- Bioprocessing (4)
- Discovery of novel compounds from sea cucumber viscera — Principal (1)
Education/Academic qualification
PhD, Flux Analysis of Baker's Yeast, University of Strathclyde
8 Sept 1976 → 30 Oct 1979
Award Date: 30 Jun 1980
Master of Science, Single Cell Protein production using Straw waste , Heriot-Watt University, Edinburgh
8 Sept 1975 → 30 Sept 1976
Award Date: 1 Oct 1976
Bachelor (Honours), Bachelor degree in Microbiology with Chemistry, St. Xavier's College, University of Bombay
4 Jul 1971 → 15 May 1975
Award Date: 15 Jul 1975
Supervision
- Registered
Research Areas
- Medical biosciences
Supervisory Interests
- Molecular plant cell-based bioprocessing
- Actinobacterial discovery
- Actinobacterial endophytes
- Pharmaceutical biotechnology and natural product drug discovery
- Bioprocess technology
- Industrial microorganisms
- Biocontrol agents
- Bioactive natural products
- Microbial diversity
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger
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SDG 3 Good Health and Well-being
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SDG 6 Clean Water and Sanitation
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SDG 7 Affordable and Clean Energy
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SDG 8 Decent Work and Economic Growth
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SDG 9 Industry, Innovation, and Infrastructure
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SDG 12 Responsible Consumption and Production
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SDG 14 Life Below Water
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SDG 15 Life on Land
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SDG 17 Partnerships for the Goals
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Collaborations and top research areas from the last five years
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Description of Streptomyces naphthomycinicus sp. nov., an endophytic actinobacterium producing naphthomycin A and its genome insight for discovering bioactive compounds
Kaewkla, O., Perkins, M., Thamchaipenet, A., Saijuntha, W., Sukpanoa, S., Suriyachadkun, C., Chamroensaksri, N., Chumroenphat, T. & Franco, C. M. M., 17 Apr 2024, In: Frontiers in Microbiology. 15, 16 p., 1353511.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)39 Downloads (Pure) -
Exploring Indonesian Sponge-Associated Marine Aspergillus hortai: Characterization of Bioactive Compounds with Potential Anti-Escherichia coli Properties
Fadillah, W. N., Sukarno, N., Iswantini, D., Rahminiwati, M., Franco, C. M. M., Zhang, W., Hanif, N. & Waite, M., Jul 2024, In: HAYATI Journal of Biosciences. 31, 4, p. 712-724 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)48 Downloads (Pure) -
Marine sponge-derived natural products: trends and opportunities for the decade of 2011-2020
Mehbub, M. F., Yang, Q., Cheng, Y., Franco, C. M. M. & Zhang, W., 26 Aug 2024, In: Frontiers in Marine Science. 11, 20 p., 1462825.Research output: Contribution to journal › Review article › peer-review
Open AccessFile33 Citations (Scopus)239 Downloads (Pure) -
Oleaginous Microbial Lipids’ Potential in the Prevention and Treatment of Neurological Disorders
Al Hattab, M., Moorthy, L. S., Patel, D., Franco, C. M. M. & Puri, M., 6 Feb 2024, In: Marine Drugs. 22, 2, 19 p., 80.Research output: Contribution to journal › Review article › peer-review
Open AccessFile11 Citations (Scopus)97 Downloads (Pure) -
Production of Alginate Oligosaccharides (AOSs) Using Enhanced Physicochemical Properties of Immobilized Alginate Lyase for Industrial Application
Kaur, S., Abraham, R. E., Franco, C. M. M. & Puri, M., Mar 2024, In: Marine Drugs. 22, 3, 14 p., 120.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)110 Downloads (Pure)