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20182023

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Personal profile

Research Interests

Beta cells, synthetic biology, optogenetics, Type I diabetes, kinases, proliferation

Research Biography

Dr Christina Gangemi received her undergraduate degree from Monash University (2016) specialising in molecular biology and biochemistry. She became an Undergraduate Research Opportunities Program Scholar (2016) and completed her Honours thesis (2017) at the Australian Regenerative Medicine Institute (ARMI), Monash University. She later joined Professor Harald Janovjak’s group at ARMI (2018) as a research assistant before completing her doctorate degree (2019-2023) where she studied optical approaches to promote pancreatic beta cell regeneration. Key achievements from this work include establishing an automated image analysis approach to quantify islet proliferation assays, designing a modular light-emitting diode shelving system for ex vivo and in vitro illumination of primary islets, generating a new assay to test cyclin-dependent kinase 6 (CDK6) function (a known beta cell proliferation driver), and exploring the effects of photoswitchable pdDronpa domains when engineered into CDK6. During her candidature, she was awarded a Juvenile Diabetes Research Foundation Australia PhD Top-Up Scholarship. She is currently a Postdoctoral Research Associate in beta cell biology at Flinders University as part of the Janovjak group. 

Education/Academic qualification

PhD, Optical approaches to promote pancreatic β-cell regeneration, Monash University

Award Date: 29 Mar 2023

Bachelor of Science (Honours), Role of the LIM homeodomain 1 (LHX1) transcription factor in germ line stem cell function, Monash University

2017

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