Research Output per year
Personal profile
Research Biography
I have a research-only role as Head of Molecular and Cellular Physiology within the Centre for Neuroscience. I undertook a post-doc with Prof. Thomas Jentsch at the ZMNH, Hamburg, Germany and was then awarded the TM Ramsay Fellowship at Prince Henry's Institute, Melbourne. I was appointed Group Leader at Flinders University as a BioInnovation SA Research Fellow in 2006. In 2010, I was awarded both a NHMRC Career Development Fellowship (Level 1) and an ARC Future Fellowship and in 2015 was awarded a NHMRC Career Development Fellowship (Level 2).
My research is focused on understanding how cells send chemical signals to each other and how this is implicated in health and disease. We have published significant work in this area in leading international journals including PLoS Genetics, Molecular Psychiatry, Gastroenterology, Human Molecular Genetics, Journal of Neuroscience, Diabetes, Nature Communications and Cell Metabolism.
My lab webpage: Molecular and Cellular Physiology Laboratory
Research Interests
The focus within my lab is identifying the molecular mechanisms controlling cell signalling and how altered cell signalling relates to human diseases; most especially related to Type 2 Diabetes, metabolism and obesity. I utilise genetic mouse models and human tissue to identify novel genes underlying aspects of these diseases and combine this with cutting edge techniques for the measurement of neurotransmitter and hormone release from single cells. This work is supported with grants from the Australian Research Council, the National Health and Medical Reseaech Council and the Diabetes Australia Research Trust.
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Research Output
Diet differentially regulates enterochromaffin cell serotonin content, density and nutrient sensitivity in the mouse small and large intestine
Martin, A. M., Jones, L. A., Jessup, C. F., Sun, E. W. & Keating, D. J., 1 Aug 2020, In : Neurogastroenterology and Motility. 32, 8, 9 p., e13869.Research output: Contribution to journal › Article
Islets and pancreatic ductal adenocarcinoma – An opportunity for translational research from the ‘Bench to the Bedside’
Barreto, S. G., Michael, M. Z. & Keating, D. J., Apr 2020, In : Pancreatology. 20, 3, p. 385-390 6 p.Research output: Contribution to journal › Review article
Mechanisms controlling hormone secretion in human gut and its relevance to metabolism
Martin, A. M., Sun, E. W. & Keating, D. J., Jan 2020, In : The Journal of endocrinology. 244, 1, p. R1-R15 15 p.Research output: Contribution to journal › Review article
Open Access
File
Abundance of Synaptic Vesicle-Related Proteins in Alpha-Synuclein-Containing Protein Inclusions Suggests a Targeted Formation Mechanism
McCormack, A., Keating, D. J., Chegeni, N., Colella, A., Wang, J. J. & Chataway, T., 15 May 2019, In : Neurotoxicity Research. 35, 4, p. 883-897 15 p.Research output: Contribution to journal › Article
Cellular regulation of peripheral serotonin
Martin, A. M., Young, R. L., Leong, L., Rogers, G. B., Spencer, N. J., Jessup, C. F. & Keating, D. J., 2019, Serotonin: The Mediator that Spans Evolution. Pilowsky, P. (ed.). Academic Press, p. 137-153 17 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter