Personal profile
Research Biography
Associate Professor Dixon is the Senior Medical Scientist in the Intensive and Critical Care Unit, Flinders Medical Centre, Associate Professor in the Dept of Critical Care Medicine, Flinders University and Head of the Lung Injury Research Laboratory. She also holds full academic status as Assoc Prof at Northen Ontario School of Medicine, Lakehead and Laurentian Universities, Canada. Assoc. Prof. Dixon obtained her PhD in Paediatrics, Flinders University in 2004 studying innate/mucosal immunology of breast milk in response to respiratory infections and allergy. Since 2004 she has continued to establish a trackrecord in innate immunology associated with acute and chronic lung injury including ALI/ARDS, infant bronchiolitis and chronic heart failure. Her success is evidenced by research funding, ~$1,430,000, as well as a publication record of >40 peer reviewed articles. Assoc. Prof. Dixon is regularly invited to review for premier international journals and to present her work at both national and international meetings.
Research Interests
Associate Professor Dani-Louise Dixon has developed a track record based on research interests in leukocyte regulation of lipid and protein mediators of innate/mucosal defence systems with particular emphasis on the lung. Assoc. Prof. Dixon provided some of the first direct evidence for the hypothesised immunological link between innate immunity in mothers and their breast-fed infants. She has established a trackrecord in laboratory studies of acute and chronic lung injury both in vitro and in vivo, as well as in clinical studies. Specific areas of interest include mediator regulation of cellular activation and infiltration of the lung and the resultant lung remodelling, and the implications on pulmonary function including respiratory mechanics and fluid regulation.
Supervised Students Successes
- May 2021 Dr James McEvoy-May - Vice Chancellor's Prize for Doctoral Thesis Excellence
- Mar 2016 Dr Shailesh Bihari - Vice-Chancellor’s Prize for Doctoral Thesis Excellence
- Jun 2013 Dr Shailesh Bihari - Finalist, Ross Wishart Award, SA ASMR
- Mar 2013 Dr Alison Elder - Finalist Channel 9 Young Achiever Award
- Mar 2013 Dr Shailesh Bihari - Clinicians Researcher Award
- Jun 2011 Dr Alison Elder - Finalist Ross Wishart Award, SA ASMR
Completed Supervisions
- Acute lung injury (1)
- Fluid administration and the lung (1)
Supervision
- Registered
Research Areas
- Clinical
Supervisory Interests
- Heart failure
- Acute lung injury
- Innate immunity
- Respiratory immunology
- Respiratory mechanics
- Bronchiolitis
- Intensive care
- Critical care medicine
- Paediatric immunology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Mechanistic Effects of Environmental and Medical Low-Dose Radiation Exposure of the Lung
Puukila, S., McEvoy-May, J., Hooker, A. M. & Dixon, D. L., Mar 2026, In: Biomedicines. 14, 3, 22 p., 644.Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Immunological and Respiratory Effects in a Healthy Rodent Model after Inhalation of Low and Regulated Levels of Radon
De Bellis, D., McEvoy-May, J., Kalnins, C., Puukila, S., Hooker, A. M., Boreham, D. & Dixon, D. L., Sept 2025, In: Radiation Research. 204, 3, p. 184-196 13 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Revisiting the monocrotaline-treated rat as a model of inflammatory lung disease: COVID-19 and future pandemic threats?
Kris, L. P., Dixon, D. L., Bihari, S. & Carr, J. M., Oct 2025, In: Animal Models and Experimental Medicine. 8, 10, p. 1785-1793 9 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus)9 Downloads (Pure) -
Evaluation of GSK2789917-induced TRPV4 inhibition in animal models of fluid induced lung injury
Bihari, S., Costell, M. H., Bouchier, T., Behm, D. J., Burgert, M., Ye, G., Bersten, A. D., Puukila, S., Cavallaro, E., Sprecher, D. L. & Dixon, D. L., May 2024, In: Naunyn-Schmiedeberg's Archives of Pharmacology. 397, 5, p. 3461-3475 15 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
The Y498T499-SARS-CoV-2 spike (S) protein interacts poorly with rat ACE2 and does not affect the rat lung
Green, A. L., De Bellis, D., Cowell, E., Lenchine, R. V., Penn, T., Kris, L. P., McEvoy-May, J., Bihari, S., Dixon, D.-L. & Carr, J. M., 2024, In: Access Microbiology. 6, 9, 13 p., 000839.v3.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)10 Downloads (Pure)
Projects
- 1 Active
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Preclinical assessment of mechanism of action in ameliorating lung injury using a novel expiratory flow regulation device for mechanical ventilation
Bihari, S. (Chief Investigator (Project Lead)), Dixon, D. (Chief Investigator), Eijkelkamp, B. (Chief Investigator), Yang, L. (Chief Investigator), Wiersema, U. (Chief Investigator), Donnelley, M. (Associate Investigator) & Kelley, N. (Associate Investigator)
1/03/25 → 28/02/27
Project: Research