Research output per year
Research output per year
Personal profile
Research Biography
Clinical Director of General and Digestive Surgery. Senior Consultant in Surgery with 23 years experience as a staff surgeon at Flinders Medical Centre and Flinders Private Hospital. Clinical interest include all aspects of general and gastrointestinal surgery, with special interests in colorectal surgery, and endoscopy and colonoscopy. Involved in trauma care at FMC as trauma consultant, and surgical representative on the trauma committee. Established world-class anorectal investigation laboratory that incorporates combined manometry, ultrasound and nerve studies of the anal sphincter mechanism. Has supervised 7 successful higher degree students in close collaboration with Prof Simon Brookes, and more recently Assoc Professors Spencer and Dinning in Human Physiology.
Research Interests
Longstanding collaboration with Professor Marcello Costa and Dr Simon Brooks in the Department of Human Physiology since 1985. Conducted doctoral and postdoctoral studies using modern techniques to study the nervous system of the human gastrointestinal tract. Made original observations on the chemistry and anatomy of this nervous system, along the length of the normal human gastrointestinal tract, and changes in this nervous system that underlie diseases such as achalasia, pyloric stenosis, gastropareseis, Hirschsprung's disease and intractable constipation. Recent observations have resulted in establishing a clinical trial to improve the function of the gastrointestinal tract in patients undergoing major abdominal surgery. This has been published in Alimentary Pharmacology and Therapeutics.
Commenced a series of studies on the effects of childbirth on the anal sphincter mechanism, and the value of biofeedback physiotherapy for the disorders of faecal incontinence and disordered defecation.
Established collaboration with the Department of General Practice and in conjunction with Dr David Weller obtained funding for a randomised trial of followup patients with colon cancer - either by their general practitioners or surgeons. This large clinical trial is now published
Supervision
- Registered
Research Areas
- Clinical
Fingerprint
Dive into the research topics where David Wattchow is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Antibody elution with 2-me/SDS solution: Uses for multi-layer immunohistochemical analysis of wholemount preparations of human colonic myenteric plexus
Humenick, A., Johnson, M. E., Chen, B. N., Wee, M., Wattchow, D. A., Costa, M., Dinning, P. G. & Brookes, S. J. H., 15 Mar 2024, In: Heliyon. 10, 5, 11 p., e26522.Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Downloads (Pure) -
Characterization of viscerofugal neurons in human colon by retrograde tracing and multi-layer immunohistochemistry
Chen, B. N., Humenick, A. G., Hibberd, T. J., Yew, W. P., Wattchow, D. A., Dinning, P. G., Costa, M., Spencer, N. J. & Brookes, S. J. H., 16 Jan 2024, In: Frontiers in Neuroscience. 17, 14 p., 1313057.Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Downloads (Pure) -
From the organ bath to the whole person: a review of human colonic motility
Wattchow, D. A., Brookes, S. J., Spencer, N. J., Heitmann, P. T., De Giorgio, R., Costa, M. & Dinning, P. G., Mar 2024, In: ANZ Journal of Surgery. 94, 3, p. 320-326 7 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus)35 Downloads (Pure) -
Alterations in GLP-1 and PYY release with aging and body mass in the human gut
Jones, L. A., Sun, E. W., Lumsden, A. L., Thorpe, D. W., Peterson, R. A., De Fontgalland, D., Sposato, L., Rabbitt, P., Hollington, P., Wattchow, D. A. & Keating, D. J., 1 Dec 2023, In: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 578, 6 p., 112072.Research output: Contribution to journal › Article › peer-review
Open AccessFile60 Downloads (Pure) -
Electrophysiological and morphological features of myenteric neurons of human colon revealed by intracellular recording and dye fills
Yew, W. P., Humenick, A., Chen, B. N., Wattchow, D. A., Costa, M., Dinning, P. G. & Brookes, S. J. H., Apr 2023, In: Neurogastroenterology and Motility. 35, 4, 13 p., e14538.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)58 Downloads (Pure)