Personal profile
Research Biography
I am Research Fellow in Virology with 8 years of experience in infectious disease research, performing mode of action and target identification studies, medium throughput screenings, computational studies and whole genome CRISPR screening with high interest in translational research. During my PhD and 1st postdoctoral role, my research focused on malaria drug discovery and the investigation of malaria protein export into the mammalian host and its effect on parasite development. In my role at Flinders, I am working on understanding the mechanism of action of a novel dengue virus inhibitor.
Supervision
- Registered
Research Areas
- Medical biosciences
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Improved quantitative structure-activity relationship (QSAR) models to predict the activity of hydroxamic acids as HDAC inhibitors against malaria parasites
Dawood, W. A., Macdonald, J. R., Skinner-Adams, T. S., Hesping, E., Gorse, A.-D. J. P. & Andrews, K. T., 5 Mar 2026, In: European Journal of Medicinal Chemistry. 305, 18 p., 118525.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Genome-wide gene expression profiles throughout human malaria parasite liver stage development in humanized mice
Zhangi, G., Patel, H., Smith, J. L., Carmago, N., Bae, Y., Hesping, E., Boddey, J. A., Venugopal, K., Marti, M., Flannery, E. L., Chuenchob, V., Fishbaugher, M. E., Mikolajczak, S. A., Roobsoong, W., Sattabongkot, J., Gupta, P., Pazzagli, L., Rezakhani, N., Betz, W. & Heyes, K. & 3 others, , Feb 2025, In: Nature Microbiology. 10, 2, p. 569–584 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)66 Downloads (Pure) -
Twelfth scientific biennial meeting of the Australasian Virology Society: AVS12 2024
Monson, E. A., Loterio, R. K., Roby, J. A., Adhikari, A., Bull, R. A., Carr, J. M., Chatzileontiadou, D. S. M., Cheng, C. X., Coulibaly, F., Davis, S. K., Deerain, J. M., Douglas, M. W., Drummer, H. E., Eyre, N. S., Freppel, W., Gowripalan, A., Grant, E. J., Gras, S., Guthmiller, J. J. & Herrero, L. J. & 19 others, , May 2025, In: Journal of Virology. 99, 5, 14 p., e02255-24.Research output: Contribution to journal › Review article › peer-review
Open AccessFile27 Downloads (Pure) -
A broadly cross-reactive i-body to AMA1 potently inhibits blood and liver stages of Plasmodium parasites
Angage, D., Chmielewski, J., Maddumage, J. C., Hesping, E., Caiazzo, S., Lai, K. H., Yeoh, L. M., Menassa, J., Opi, D. H., Cairns, C., Puthalakath, H., Beeson, J. G., Kvansakul, M., Boddey, J. A., Wilson, D. W., Anders, R. F. & Foley, M., 22 Aug 2024, In: Nature Communications. 15, 1, 17 p., 7206.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)58 Downloads (Pure) -
MAM 2024: Malaria in a changing world
Longley, R. J., Malinga, J., Hesping, E., Sutanto, E., DonVito, S. M., Kucharski , M., Oyong, D. A., Verhoef, J. M. J., Du, E., Villasis, E. & Mwikali, K., May 2024, In: Trends in Parasitology. 40, 5, p. 355-361 7 p.Research output: Contribution to journal › Comment/debate
7 Citations (Scopus)