Research output per year
Research output per year
Personal profile
Research Biography
Based at Flinders University and SAHMRI, my research harnesses the power of large-scale molecular data to understand the hidden forces that shape human health, from the gut bacteria that prime a newborn’s immune system, to the molecular drivers of chronic diseases such as long COVID.
I have co-authored over 50 peer-reviewed publications in the world’s top scientific journals including Nature and Science, accumulating more than 6,000 citations globally. Recognised on the Stanford/Elsevier list of the world’s top 2% of scientists, my discoveries have sparked clinical trials and have been cited in health policy guidelines issued by governments and health authorities across the UK, US, Germany, the European Union, and the World Health Organisation.
Supervision
- Registered
Research Areas
- Medical biosciences
- Molecular biosciences
Supervisory Interests
- Multi-omics
- Microbiome
- Bioinformatics
- Cancer biology
- Genomics
- Infection and immunity
- Virology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger -
SDG 3 Good Health and Well-being -
SDG 11 Sustainable Cities and Communities
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Bladder mucosal afferents detect UTI and aid pathogen clearance
Tay, C., Sharma, H., Ramsay, S., Bourlotos, G., Manning, S. K., Stevens, N. E., Miller, S. J., Rogers, G. B., Lynn, D. J., Ryan, F. J., Harrington, A. M., Zagorodnyuk, V., Taylor, S. L. & Grundy, L., 11 Aug 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 32, 11 p., e2604124123.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Pre-treatment gut microbiome and salivary metabolome signatures associate with chemotherapy-induced cognitive decline in women with breast cancer: A prospective pilot study
Cross, C. B., Bowen, J. M., Leifert, W. R., Beale, D. J., Francois, M., Joshi, R., Fosh, B. G., Coller, J. K., Tuke, J., Bareham, M., Cosier, D. J., To, L. H., Ryan, F. J. & Wardill, H. R., 1 Mar 2026, In: Cancer Letters. 640, 5 p., 218234.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
The gut–heart axis in cardio-oncology
Chan, N. S. L., Cross, C., Bowen, J., Prestidge, C., Ryan, F. J., Dorraki, M., Liyanage, S., Sharma, S., Pathy, R., Bursill, C. A., Psaltis, P. J., Marques, F. Z., Wardill, H. R. & Joyce, P., Aug 2026, In: Cardiovascular Research. 122, 12, p. 1573-1588 16 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus) -
Total RNA and MicroRNA Transcriptomic Responses of Human Retinal Müller Glial Cells to Infection with Toxoplasma gondii Tachyzoites
Rochet, E., Ryan, F. J., Ma, Y., Ashander, L. M., Marri, S., Matthews, J. M., Furtado, J. M., Appukuttan, B., Lynn, D. J. & Smith, J. R., Jan 2026, In: Ophthalmology Science. 6, 1, 16 p., 100971.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Acute urinary tract infection elicits bladder afferent hypersensitivity
Sharma, H., Manning, S. K., Stevens, N. E., Bourlotos, G., Ryan, F. J., Tay, C., Klebe, S., Rogers, G. B., Lynn, D. J., Taylor, S. L. & Grundy, L., Mar 2025, In: Brain, Behavior, and Immunity - Health. 44, 6 p., 100944.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)59 Downloads (Pure)
Projects
- 4 Active
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Developing a new strategy to reduce the side effects of bladder cancer treatment
Grundy, L. (Chief Investigator (Project Lead)), Lynn, D. (Associate Investigator), Ryan, F. (Associate Investigator), Selth, L. (Associate Investigator), Hong, M. (Associate Investigator), Kichenadasse, G. (Associate Investigator) & Plagakis, S. A. (Associate Investigator)
1/10/25 → 30/09/28
Project: Research
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Advancing Blood-Based Diagnostics for Blood-Brain Barrier Disruption in Stroke Using Next- Generation Molecular Tools
Ryan, F. (Chief Investigator (Project Lead)), Hood , R. (Chief Investigator), Stuckey, S. (Chief Investigator), Turner, R. (Chief Investigator), Jukes, A. (Associate Investigator) & Tay, S. (Associate Investigator)
26/06/25 → 31/12/26
Project: Research
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Relaxing the bladder: A novel adjunct strategy to improve bladder cancer survivorship
Grundy, L. (Chief Investigator (Project Lead)), Hong, M. (Chief Investigator), Ryan, F. (Chief Investigator), Plagakis, S. (Associate Investigator) & Kichenadasse, G. (Associate Investigator)
1/03/25 → 28/02/27
Project: Research
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How do microbes interact with human host cells during the early stages of tumour formation?
Roach, M. (Chief Investigator (Project Lead)), Falk, N. (Chief Investigator), Hollington, P. (Chief Investigator), Mallawaarachchi, V. (Chief Investigator), Edwards, R. (Chief Investigator), Symonds, E. (Associate Investigator), Winter, J. (Associate Investigator), Laven-Law, G. (Associate Investigator), Kichenadasse, G. (Associate Investigator) & Ryan, F. (Associate Investigator)
1/03/25 → 28/02/27
Project: Research