- Anti-cancer radiotherapy and chemotherapy can cause early menopause and infertility. This research area is about developing approaches to preserving the fertility of female cancer survivors.
Medical Biotechnology and Reproductive Toxicology
- The early lab-based development of therapies with the potential to prevent breast, uterine and ovarian cancer.
- The use of human reproductive cells in vitro (including primary-derived human granulosa cells and spermatozoa, embryonic stem cells, and human breast, uterine and ovarian cancer cell lines), as well as in vitro mouse cultures, to assess the toxicity, or the activity, of novel bioactive extracts, nanoparticles, agrichemicals (eg pesticides and herbicides), new pharmaceutical agents or bioremediation products.
- Development and application of 3D cell culture methods, and their application to developing novel contraceptives.
- The development and application of assays to detect and quantify endocrine disrupting compounds (EDCs) in surface and drinking waters, recycled water and wastewater, using SPE-ELISA, HPLC, E-screen, and human cell lines in novel in vitro assays.
- The characterisation of particles in wastewater, and their effects on recycling