Research output per year
Research output per year
- 1 - 50 out of 62 results
Search results
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2022
Light-activated receptor tyrosine kinases: Designs and applications
Crossman, S. H. & Janovjak, H., Apr 2022, In: Current Opinion in Pharmacology. 63, 7 p., 102197.Research output: Contribution to journal › Review article › peer-review
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Optogenetic neuroregeneration
Janovjak, H. & Kleinlogel, S., Jul 2022, In: Neural Regeneration Research. 17, 7, p. 1468-1470 3 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
2021
Acute and chronic effects of a light-activated FGF receptor in keratinocytes in vitro and in mice
Rauschendorfer, T., Gurri, S., Heggli, I., Maddaluno, L., Meyer, M., Inglés-Prieto, Á., Janovjak, H. & Werner, S., Nov 2021, In: Life Science Alliance. 4, 11, 12 p., e202101100.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)6 Downloads (Pure) -
A Light-Oxygen-Voltage Receptor Integrates Light and Temperature
Dietler, J., Schubert, R., Krafft, T. G. A., Meiler, S., Kainrath, S., Richter, F., Schweimer, K., Weyand, M., Janovjak, H. & Möglich, A., 23 Jul 2021, In: Journal of Molecular Biology. 433, 15, 20 p., 167107.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
A Rationally and Computationally Designed Fluorescent Biosensor for d -Serine
Vongsouthi, V., Whitfield, J. H., Unichenko, P., Mitchell, J. A., Breithausen, B., Khersonsky, O., Kremers, L., Janovjak, H., Monai, H., Hirase, H., Fleishman, S. J., Henneberger, C. & Jackson, C. J., 26 Nov 2021, In: ACS Sensors. 6, 11, p. 4193-4205 13 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Formation of Kiss1R/GPER Heterocomplexes Negatively Regulates Kiss1R-mediated Signalling through Limiting Receptor Cell Surface Expression
Ke, R., Lok, S. I. S., Singh, K., Chow, B. K. C., Janovjak, H. & Lee, L. T. O., 2 Apr 2021, In: Journal of Molecular Biology. 433, 7, 16 p., 166843.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Microbial methionine transporters and biotechnological applications
Mohany, N. A. M., Totti, A., Naylor, K. R. & Janovjak, H., May 2021, In: Applied Microbiology and Biotechnology. 105, 10, p. 3919-3929 11 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Optogenetic delivery of trophic signals in a genetic model of Parkinson’s disease
Ingles-Prieto, A., Furthmann, N., Crossman, S. H., Tichy, A. M., Hoyer, N., Petersen, M., Zheden, V., Biebl, J., Reichhart, E., Gyoergy, A., Siekhaus, D. E., Soba, P., Winklhofer, K. F. & Janovjak, H., 15 Apr 2021, In: PloS Genetics. 17, 4 April 2021, 23 p., e1009479.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus) -
2020
All-Optical Miniaturized Co-culture Assay of Voltage-Gated Ca2+ Channels
Agus, V. & Janovjak, H., 2020, Photoswitching Proteins: Methods and Protocols. Niopek, D. (ed.). Humana Press Inc., p. 247-260 14 p. (Methods in Molecular Biology; vol. 2173).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
1 Citation (Scopus) -
Design and Application of Light-Regulated Receptor Tyrosine Kinases
Kainrath, S. & Janovjak, H., 2020, Photoswitching Proteins: Methods and Protocols. Niopek, D. (ed.). Humana Press Inc., p. 233-246 14 p. (Methods in Molecular Biology; vol. 2173).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
3 Citations (Scopus) -
LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia
Henneberger, C., Bard, L., Panatier, A., Reynolds, J. P., Kopach, O., Medvedev, N. I., Minge, D., Herde, M. K., Anders, S., Kraev, I., Heller, J. P., Rama, S., Zheng, K., Jensen, T. P., Sanchez-Romero, I., Jackson, C. J., Janovjak, H., Ottersen, O. P., Nagelhus, E. A., Oliet, S. H. R. & 3 others, , 9 Dec 2020, In: NEURON. 108, 5, p. 919-936.e11 30 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile50 Citations (Scopus)3 Downloads (Pure) -
Optogenetic control of excitatory post-synaptic differentiation through neuroligin-1 tyrosine phosphorylation
Letellier, M., Lagardère, M., Tessier, B., Janovjak, H. & Thoumine, O., 23 Apr 2020, In: eLife. 9, 21 p., e52027.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)2 Downloads (Pure) -
2019
Editorial overview: Synthetic sensors and signals — new tools for a new trade
Möglich, A. & Janovjak, H., Aug 2019, In: Current Opinion in Structural Biology. 57, p. iii-v 3 p.Research output: Contribution to journal › Editorial
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Engineering Strategy and Vector Library for the Rapid Generation of Modular Light-Controlled Protein–Protein Interactions
Tichy, A. M., Gerrard, E. J., Legrand, J. M. D., Hobbs, R. M. & Janovjak, H., 9 Aug 2019, In: Journal of Molecular Biology. 431, 17, p. 3046-3055 10 p.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Isolation of synaptic vesicles from genetically engineered cultured neurons
McKenzie, C., Spanova, M., Johnson, A., Kainrath, S., Zheden, V., Sitte, H. H. & Janovjak, H., 15 Jan 2019, In: Journal of Neuroscience Methods. 312, p. 114-121 8 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Light-activated chimeric GPCRs: limitations and opportunities
Tichy, A. M., Gerrard, E. J., Sexton, P. M. & Janovjak, H., Aug 2019, In: Current Opinion in Structural Biology. 57, p. 196-203 8 p.Research output: Contribution to journal › Review article › peer-review
10 Citations (Scopus) -
Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm cell migration
Čapek, D., Smutny, M., Tichy, A. M., Morri, M., Janovjak, H. & Heisenberg, C. P., 16 Jan 2019, In: eLife. 8, 24 p., e42093.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus) -
2018
Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS
Zhang, W. H., Herde, M. K., Mitchell, J. A., Whitfield, J. H., Wulff, A. B., Vongsouthi, V., Sanchez-Romero, I., Gulakova, P. E., Minge, D., Breithausen, B., Schoch, S., Janovjak, H., Jackson, C. J. & Henneberger, C., 1 Sep 2018, In: Nature Chemical Biology. 14, 9, p. 861-869 9 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
Optical functionalization of human Class A orphan G-protein-coupled receptors
Morri, M., Sanchez-Romero, I., Tichy, A. M., Kainrath, S., Gerrard, E. J., Hirschfeld, P. P., Schwarz, J. & Janovjak, H., 1 Dec 2018, In: Nature Communications. 9, 1, 1950.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (Scopus) -
2017
Ancestral Protein Reconstruction and Circular Permutation for Improving the Stability and Dynamic Range of FRET Sensors
Clifton, B. E., Whitfield, J. H., Sanchez-Romero, I., Herde, M. K., Henneberger, C., Janovjak, H. & Jackson, C. J., 2017, Synthetic Protein Switches: Methods and Protocols. Stein, V. (ed.). New York: Humana Press Inc., p. 71-87 17 p. (Methods in Molecular Biology; vol. 1596).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
6 Citations (Scopus) -
Green-Light-Induced Inactivation of Receptor Signaling Using Cobalamin-Binding Domains
Kainrath, S., Stadler, M., Reichhart, E., Distel, M. & Janovjak, H., 10 Apr 2017, In: Angewandte Chemie - International Edition. 56, 16, p. 4608-4611 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile59 Citations (Scopus) -
Method for Developing Optical Sensors Using a Synthetic Dye-Fluorescent Protein FRET Pair and Computational Modeling and Assessment
Mitchell, J. A., Zhang, W. H., Herde, M. K., Henneberger, C., Janovjak, H., O’Mara, M. L. & Jackson, C. J., 2017, Synthetic Protein Switches: Methods and Protocols. Stein, V. (ed.). New York: Humana Press Inc., p. 89-99 11 p. (Methods in Molecular Biology; vol. 1596).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
1 Citation (Scopus) -
Optogenetic methods in drug screening: technologies and applications
Agus, V. & Janovjak, H., 1 Dec 2017, In: CURRENT OPINION IN BIOTECHNOLOGY. 48, p. 8-14 7 p.Research output: Contribution to journal › Review article › peer-review
12 Citations (Scopus) -
2016
A Phytochrome Sensory Domain Permits Receptor Activation by Red Light
Reichhart, E., Ingles-Prieto, A., Tichy, A. M., McKenzie, C. & Janovjak, H., 17 May 2016, In: Angewandte Chemie - International Edition. 55, 21, p. 6339-6342 4 p.Research output: Contribution to journal › Article › peer-review
53 Citations (Scopus) -
Light at the End of the Protein: Crystal Structure of a C-Terminal Light-Sensing Domain
Janovjak, H., 2 Feb 2016, In: STRUCTURE. 24, 2, p. 213-215 3 p.Research output: Contribution to journal › Short survey › peer-review
Open Access1 Citation (Scopus) -
Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation
Sako, K., Pradhan, S. J., Barone, V., Inglés-Prieto, Á., Müller, P., Ruprecht, V., Čapek, D., Galande, S., Janovjak, H. & Heisenberg, C. P., 19 Jul 2016, In: Cell Reports. 16, 3, p. 866-877 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile65 Citations (Scopus) -
Rangefinder: A Semisynthetic FRET Sensor Design Algorithm
Mitchell, J. A., Whitfield, J. H., Zhang, W. H., Henneberger, C., Janovjak, H., O'Mara, M. L. & Jackson, C. J., 23 Nov 2016, In: ACS Sensors. 1, 11, p. 1286-1290 5 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
2015
Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction
Whitfield, J. H., Zhang, W. H., Herde, M. K., Clifton, B. E., Radziejewski, J., Janovjak, H., Henneberger, C. & Jackson, C. J., Sep 2015, In: Protein Science. 24, 9, p. 1412-1422 11 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Citations (Scopus) -
Flipping the Photoswitch: Ion Channels Under Light Control
McKenzie, C. K., Sanchez-Romero, I. & Janovjak, H., 2015, Novel Chemical Tools to Study Ion Channel Biology. Ahern, C. & Pless, S. (eds.). Vol. 869. p. 101-117 17 p. (Advances in Experimental Medicine and Biology).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
8 Citations (Scopus) -
Light-assisted small-molecule screening against protein kinases
Inglés-Prieto, Á., Reichhart, E., Muellner, M. K., Nowak, M., Nijman, S. M. B., Grusch, M. & Janovjak, H., Dec 2015, In: Nature Chemical Biology. 11, 12, p. 952-954 3 p.Research output: Contribution to journal › Article › peer-review
37 Citations (Scopus) -
Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection
Hühner, J., Ingles-Prieto, Á., Neusüß, C., Lämmerhofer, M. & Janovjak, H., Feb 2015, In: Electrophoresis. 36, 4, p. 518-525 8 p.Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
2014
Spatio-temporally precise activation of engineered receptor tyrosine kinases by light
Grusch, M., Schelch, K., Riedler, R., Reichhart, E., Differ, C., Berger, W., Inglés-Prieto, Á. & Janovjak, H., 1 Aug 2014, In: EMBO Journal. 33, 15, p. 1713-1726 14 p.Research output: Contribution to journal › Article › peer-review
Open Access156 Citations (Scopus) -
The optogenetic promise for oncology: Episode I
Ingles-Prieto, A., Reichhart, E., Schelch, K., Janovjak, H. & Grusch, M., 2014, In: Molecular and Cellular Oncology. 1, 4, 4 p., e964045.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus) -
2013
Optical Control of Ligand-Gated Ion Channels
Szobota, S., McKenzie, C. & Janovjak, H., 2013, Ion Channels: Methods and Protocols. Gamper, N. (ed.). p. 417-435 19 p. (Methods in Molecular Biology; vol. 998).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
2 Citations (Scopus) -
Optical control of metabotropic glutamate receptors
Levitz, J., Pantoja, C., Gaub, B., Janovjak, H., Reiner, A., Hoagland, A., Schoppik, D., Kane, B., Stawski, P., Schier, A. F., Trauner, D. & Isacoff, E. Y., Apr 2013, In: NATURE NEUROSCIENCE. 16, 4, p. 507-516 10 p.Research output: Contribution to journal › Article › peer-review
156 Citations (Scopus) -
2011
A modern ionotropic glutamate receptor with a K+ selectivity signature sequence
Janovjak, H., Sandoz, G. & Isacoff, E. Y., 8 Mar 2011, In: Nature Communications. 2, 1, 5 p., 232.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
Structure-based design of light-controlled proteins
Janovjak, H. & Isacoff, E. Y., 2011, Photosensitive Molecules for Controlling Biological Function. Chambers, J. & Kramer, R. (eds.). p. 233-266 34 p. (Neuromethods; vol. 55).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
1 Citation (Scopus) -
2010
A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing
Janovjak, H., Szobota, S., Wyart, C., Trauner, D. & Isacoff, E. Y., Aug 2010, In: NATURE NEUROSCIENCE. 13, 8, p. 1027-1032 6 p.Research output: Contribution to journal › Article › peer-review
108 Citations (Scopus) -
Pharmacology of ionotropic glutamate receptors: A structural perspective
Stawski, P., Janovjak, H. & Trauner, D., 15 Nov 2010, In: Bioorganic and Medicinal Chemistry. 18, 22, p. 7759-7772 14 p.Research output: Contribution to journal › Review article › peer-review
47 Citations (Scopus) -
2009
Periodic Forces Trigger a Complex Mechanical Response in Ubiquitin
Szymczak, P. & Janovjak, H., 17 Jul 2009, In: Journal of Molecular Biology. 390, 3, p. 443-456 14 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
2008
From valleys to ridges: Exploring the dynamic energy landscape of single membrane proteins
Janovjak, H., Sapra, K. T., Kedrov, A. & Müller, D. J., 2 May 2008, In: Chemphyschem. 9, 7, p. 954-966 13 p.Research output: Contribution to journal › Review article › peer-review
39 Citations (Scopus) -
Fully automated single-molecule force spectroscopy for screening applications
Struckmeier, J., Wahl, R., Leuschner, M., Nunes, J., Janovjak, H., Geisler, U., Hofmann, G., Jähnke, T. & Müller, D. J., 24 Sep 2008, In: Nanotechnology. 19, 38, 384020.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus) -
2007
Deciphering molecular interactions of native membrane proteins by single-molecule force spectroscopy
Kedrov, A., Janovjak, H., Sapra, K. T. & Müller, D. J., 9 Jun 2007, In: Annual Review of Biophysics and Biomolecular Structure. 36, p. 233-260 28 p.Research output: Contribution to journal › Review article › peer-review
104 Citations (Scopus) -
Digital force-feedback for protein unfolding experiments using atomic force microscopy
Bippes, C. A., Janovjak, H., Kedrov, A. & Muller, D. J., 31 Jan 2007, In: Nanotechnology. 18, 4, 044022.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Free energy of membrane protein unfolding derived from single-molecule force measurements
Preiner, J., Janovjak, H., Rankl, C., Knaus, H., Cisneros, D. A., Kedrov, A., Kienberger, F., Muller, D. J. & Hinterdorfer, P., 1 Aug 2007, In: Biophysical Journal. 93, 3, p. 930-937 8 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Citations (Scopus) -
Transmembrane helices have rough energy surfaces
Janovjak, H., Knaus, H. & Muller, D. J., 1 Jan 2007, In: Journal of The American Chemical Society. 129, 2, p. 246-247 2 p.Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus) -
2006
Bacteriorhodopsin folds into the membrane against an external force
Kessler, M., Gottschalk, K. E., Janovjak, H., Muller, D. J. & Gaub, H. E., 24 Mar 2006, In: Journal of Molecular Biology. 357, 2, p. 644-654 11 p.Research output: Contribution to journal › Article › peer-review
82 Citations (Scopus) -
Direct measurement of single-molecule visco-elasticity in atomic force microscope force-extension experiments
Bippes, C. A., Humphris, A. D. L., Stark, M., Müller, D. J. & Janovjak, H., Feb 2006, In: European Biophysics Journal. 35, 3, p. 287-292 6 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Imaging and detecting molecular interactions of single transmembrane proteins
Janovjak, H., Kedrov, A., Cisneros, D. A., Sapra, K. T., Struckmeier, J. & Muller, D. J., Apr 2006, In: Neurobiology of Aging. 27, 4, p. 546-561 16 p.Research output: Contribution to journal › Review article › peer-review
32 Citations (Scopus) -
Observing folding pathways and kinetics of a single sodium-proton antiporter from Escherichia coli
Kedrov, A., Janovjak, H., Ziegler, C., Kuhlbrandt, W. & Muller, D. J., 6 Jan 2006, In: Journal of Molecular Biology. 355, 1, p. 2-8 7 p.Research output: Contribution to journal › Article › peer-review
37 Citations (Scopus)