Research output per year
Research output per year
Personal profile
Research Biography
Jianling is a biochemist who has studied the cellular signalling pathways that involve mTOR, a master regulator of cell anabolism. He has built up a continuous track record based on mTOR-related publications, and has authored 40 peer-reviewed publications, including 18 first/last author papers in top-ranking journals; e.g. Curr Biol, Cell Mol Life Sci, Diabetologia, Int J Cancer, J Biol Chem, Mol Cell Biol, J Mol Biol, among others. His articles has thus far been cited 1321 times (search date: 07/08/2020, Google Scholar). Most of these papers are related to protein synthesis/mRNA translation, tumour growth/survival/metastasis and pancreatic β-cell functions. He also hold two patents and authored two book chapters and has given 8 presentations at international conferences. He recently joint A/Prof. Luke Selth's lab at Flinders Centre for Innovation in Cancer and his research interests have now evolved towards studying the regulation of mRNA translation in prostate cancer progression.
Education/Academic qualification
University of Leicester, Leicester
Award Date: 13 Jul 2012
Keywords
- RM Therapeutics. Pharmacology
- biochemistry
- physiology
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Research output
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Bicuculline regulated protein synthesis is dependent on Homer1 and promotes its interaction with eEF2K through mTORC1-dependent phosphorylation
Gladulich, L. F. H., Xie, J., Jensen, K. B., Kamei, M., Paes-de-Carvalho, R., Cossenza, M. & Proud, C. G., 6 Sep 2020, (E-pub ahead of print) In: Journal of Neurochemistry. 16 p.Research output: Contribution to journal › Article › peer-review
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Eukaryotic elongation factor 2 kinase promotes angiogenesis in hepatocellular carcinoma via PI3K/Akt and STAT3
Zhou, Y., Li, Y., Xu, S., Lu, J., Zhu, Z., Chen, S., Tan, Y., He, P., Xu, J., Proud, C. G., Xie, J. & Shen, K., 1 Mar 2020, In: International Journal of Cancer. 146, 5, p. 1383-1395 13 p.Research output: Contribution to journal › Article › peer-review
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MAPK-interacting kinase 2 (MNK2) regulates adipocyte metabolism independently of its catalytic activity
Merrett, J. E., Xie, J., Psaltis, P. J. & Proud, C. G., 31 Jul 2020, In: The Biochemical journal. 477, 14, p. 2735-2754 20 p.Research output: Contribution to journal › Article › peer-review
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Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis
Xie, J., Shen, K., Jones, A. T., Yang, J., Tee, A. R., Shen, M. H., Yu, M., Irani, S., Wong, D., Merrett, J. E., Lenchine, R. V., De Poi, S., Jensen, K. B., Trim, P. J., Snel, M. F., Kamei, M., Martin, S. K., Fitter, S., Tian, S., Wang, X. & 3 others, , 13 Mar 2020, (E-pub ahead of print) In: Cellular and Molecular Life Sciences. 78, 1, p. 249-270 22 p.Research output: Contribution to journal › Article › peer-review
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The eEF2 kinase-induced STAT3 inactivation inhibits lung cancer cell proliferation by phosphorylation of PKM2
Xiao, M., Xie, J., Wu, Y., Wang, G., Qi, X., Liu, Z., Wang, Y., Wang, X., Hoque, A., Oakhill, J., Proud, C. G. & Li, J., 13 Feb 2020, In: Cell Communication and Signaling. 18, 1, 14 p., 25.Research output: Contribution to journal › Article › peer-review
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