Personal profile
Research Biography
Karen obtained her BSc (Hons) degree from Flinders University in 1997. She then went on to carry out her PhD research at Adelaide University, based at the Women's and Children's Hospital, in the area of neurogenetics. During this time her research was in the identification of genes involved in intellectual disability, culminating in the identification of genes for 2 disorders (BFLS and ARX). Following her PhD studies, Karen was awarded a Nuffield Medical Research Fellowship, enabling her to take up a post-doctoral research position at Oxford University, UK. During her time in Oxford, Karen's research was predominantly in the field of gene regulation and chromatin remodeling, in addition to lecturing and tutoring medical students in Medical Genetics and Biochemistry at Oxford University. After spending 7 years in the UK, Karen returned to Flinders University in 2010 to continue both teaching and research in human genetics. In addition to developing and coordinating all undergraduate human genetics topics at Flinders, Karen has also played a key role in the implementation of Team Based Learning in the MD degree.
Research Interests
Supervision
- Registered
Research Areas
- Medical biosciences
Supervisory Interests
- Cancer genetics
- Chromatin gene regulation
- Gene expression
- Disease gene identification
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Transforming education-focused academic roles in higher education: a scoping review
Keyhanfar, M., Guensche, S., Hill, E., Brown, S., Lower, K. & King, S., 1 Oct 2025, p. 41. 1 p.Research output: Contribution to conference › Abstract
Open Access -
Brief research report: ETS-1 blockade increases ICAM-1 expression in activated human retinal endothelial cells
Tan, A. C. R., Ma, Y., Appukuttan, B., Lower, K., Lumsden, A. L., Michael, M. Z., Smith, J. R. & Ashander, L. M., 16 Apr 2024, In: Frontiers in Ophthalmology. 4, 7 p., 1384428.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)70 Downloads (Pure) -
Lipid uptake in chronic lymphocytic leukemia
Thurgood, L. A., Best, O. G., Rowland, A., Lower, K. M., Brooks, D. A. & Kuss, B. J., Feb 2022, In: Experimental Hematology. 106, p. 58-67 10 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (Scopus) -
A biclonal case of chronic lymphocytic leukaemia with discordant mutational status of the immunoglobulin heavy chain variable region and bimodal CD49d expression
Hotinski,, A. K., Best, O. G., Thurgood,, L. A., Lower, K. M. & Kuss, B. J., Feb 2021, In: British Journal of Haematology. 192, 3, p. e77-e81 4 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Insight into del17p low-frequency subclones in chronic lymphocytic leukaemia (CLL): data from the Australasian Leukaemia and Lymphoma Group (ALLG)/CLL Australian Research Consortium (CLLARC) CLL5 trial
Do, C., Best, O. G., Thurgood, L., Hotinski, A., Apostolou, S., Mulligan, S. P., Lower, K. & Kuss, B., May 2021, In: British Journal of Haematology. 193, 3, p. 556-560 5 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)
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Examining the Teaching Specialist (TS) role: Definitions, policies and practices
King, S. (Speaker), Morello, A. (Speaker), Murray, A. (Speaker), Lower, K. (Speaker) & Keyhanfar, M. (Speaker)
2022Activity: Talk or presentation types › Oral presentation
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Festival of Learning and Teaching
Cornelius-Bell, A. (Chair), Lower, K. (Participant), Murray, A. (Participant) & Rankin, J. (Participant)
10 Nov 2020Activity: Participating in or organising an event types › Organising a conference, workshop, ...