• 1917 Citations
  • 25 h-Index
20022020

Research output per year

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Personal profile

Research Biography

I have been fascinated by molecular biology since first undertaking a Biotechnology degree at Flinders University. I subsequently completed a PhD at University of Adelaide and then conducted post-doctoral studies at Cancer Research UK’s London Research Institute, widely considered to be one of the premier basic cancer research institutes in the world. As a recipient of a prestigious European Molecular Biology Organization long-term fellowship, I studied epigenetic mechanisms underlying transcriptional deregulation in cancer and developed expertise in contemporary molecular, biochemical and omic techniques.

Upon returning to Adelaide in 2009, I subsequently received Young Investigator Awards from the Prostate Cancer Foundation of Australia (PCFA) and the Prostate Cancer Foundation, the latter the only awarded to an Australian-based researcher (of >280 total since 2007). In 2015 I established an independent lab group at the University of Adelaide, which I transferred to Flinders University in 2019. My research is focused on two broad themes: a) elucidating the changes that occur to the androgen receptor signaling axis during prostate cancer progression, and using this information to identify novel opportunities for AR-based and AR-independent therapies; b) investigating the role of non-coding RNAs in prostate cancer metastasis and their potential as biomarkers of disease. I regularly publish my research in top-tier journals, including recent papers in Cancer ResearchEuropean UrolScience Translational Medicine, Journal of the National Cancer InstituteEMBO JournalOncogene, and Nucleic Acids Research.

Education/Academic qualification

Bachelor (Honours), Flinders University

PhD, University of Adelaide

External positions

Adjunct Associate Professor, University of Adelaide

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Research Output

Open Access
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  • 9 Downloads (Pure)

    New Opportunities for Targeting the Androgen Receptor in Prostate Cancer

    Centenera, M. M., Selth, L. A., Ebrahimie, E., Butler, L. M. & Tilley, W. D., Jan 2020, In : Cold Spring Harbor perspectives in medicine. 8, 12, a030478.

    Research output: Contribution to journalReview article

  • The epigenetic and transcriptional landscape of neuroendocrine prostate cancer

    Davies, A., Zoubeidi, A. & Selth, L. A., Feb 2020, In : Endocrine-Related Cancer. 27, 2, p. R35-R50 16 p.

    Research output: Contribution to journalReview article

    Open Access
  • 2 Citations (Scopus)

    A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

    Warren, A. Y., Massie, C. E., Watt, K., Luko, K., Orafidiya, F., Selth, L. A., Mohammed, H., Chohan, B. S., Menon, S., Baridi, A., Zhao, W., Escriu, C., Pungsrinont, T., D’Santos, C., Yang, X., Taylor, C., Qureshi, A., Zecchini, V. R., Shaw, G. L., Dehm, S. M. & 7 others, Mills, I. G., Carroll, J. S., Tilley, W. D., McEwan, I. J., Baniahmad, A., Neal, D. E. & Asim, M., 14 Feb 2019, In : Oncogene. 38, p. 1136-1150 15 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 3 Citations (Scopus)
    5 Downloads (Pure)

    Grainyhead-like-2 confers NK-sensitivity through interactions with epigenetic modifiers

    MacFawn, I., Wilson, H., Selth, L. A., Leighton, I., Serebriiskii, I., Bleackley, R. C., Elzamzamy, O., Farris, J., Pifer, P. M., Richer, J. & Frisch, S. M., Jan 2019, In : Molecular Immunology. 105, p. 137-149 13 p.

    Research output: Contribution to journalArticle

  • 7 Citations (Scopus)