Research output per year
Research output per year
Personal profile
Research Biography
My current research encompasses treatment strategies and biomarker discovery for Motor Neuron Disease (also known as Amyotrophic Lateral Sclerosis).
After completing a PhD at Adelaide University in December 2003, I undertook postdoctoral studies in the Neurotrophic Laboratory at Flinders University. I now lead the research undertaken in the Neurotrophic Laboratory.
ORCID https://orcid.org/0000-0002-3482-8741
My lab webpage can be found at: http://www.flinders.edu.au/neuroscience/lab_mnd.html
Research Interests
Motor Neuron Disease - developing novel treatment strategies, biomarkers and causative factors for motor neuron disease.
Neurotrophins and neurotrophin receptors - how they function in the nervous system and immune system.
Supervised Students Successes
- Apr 2016 Stephanie Shepheard - Vice Chancellor's Prize for Thesis excellence
- Dec 2015 Kevin Smith - Novartis Pharmaceuticals Postgraduate Seminar Prize
- Oct 2015 Kevin Smith - Poster Prize, Flinders University School of Medicine PhD Student Day
- Dec 2014 Stephanie Shepheard - Flinders University Centre for Neuroscience Kathleen V. Russell Prize in Neurobiology
- Dec 2014 Kevin Smith - Highly Commended Poster Prize, International ALS/MND Symposium, Brussels, Belgium
- Sep 2013 Stephanie Shepheard - Poster Prize, Flinders University Centre for Neuroscience Collaborators Day 2013
Completed Supervisions
Principal Supervisions:
- Motor Neuron Disease Biomarkers (1)
- Targeted Gene Therapy for Motor Neuron Disease (1)
Associate Supervisions:
- Motor Neuron Biology (1)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Supervision
- Registered
Research Areas
- Medical biosciences
Supervisory Interests
- Neuroscience
- Motor neuron disease
- Biomarker discovery
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Prognostic clinical and biological markers for amyotrophic lateral sclerosis disease progression: validation and implications for clinical trial design and analysis
Benatar, M., Macklin, E. A., Malaspina, A., Rogers, M. L., Hornstein, E., Lombardi, V., Renfrey, D., Shepheard, S., Magen, I., Cohen, Y., Granit, V., Statland, J. M., Heckmann, J. M., Rademakers, R., McHutchison, C. A., Petrucelli, L., McMillan, C. T., Wuu, J. & CReATe Consortium PGB1 Study Investigators, Oct 2024, In: EBioMedicine. 108, 15 p., 105323.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)27 Downloads (Pure) -
Safety, tolerability, and efficacy of fasudil in amyotrophic lateral sclerosis (ROCK-ALS): a phase 2, randomised, double-blind, placebo-controlled trial
Koch, J. C., Leha, A., Bidner, H., Cordts, I., Dorst, J., Günther, R., Zeller, D., Braun, N., Metelmann, M., Corcia, P., De La Cruz, E., Weydt, P., Meyer, T., Großkreutz, J., Soriani, M. H., Attarian, S., Weishaupt, J. H., Weyen, U., Kuttler, J. & Zurek, G. & 15 others, , Nov 2024, In: The Lancet Neurology. 23, 11, p. 1133-1146 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)15 Downloads (Pure) -
Sustainability-Driven Accelerated Shear-Mediated Immunoassay for Amyotrophic Lateral Sclerosis Detection
Luo, X., Heydari, A., Renfrey, D., Gardner, Z., He, S., Tang, Y., Weiss , G., Rogers, M.-L. & Raston, C., 11 Nov 2024, In: ChemSusChem. 17, 21, 14 p., e202401008.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)10 Downloads (Pure) -
Biomarkers for predicting disease course in Sanfilippo syndrome: An urgent unmet need in childhood-onset dementia
Winner, L. K., Rogers, M.-L., Snel, M. F. & Hemsley, K. M., Aug 2023, In: Journal of Neurochemistry. 166, 3, p. 481-496 16 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile7 Citations (Scopus)166 Downloads (Pure) -
Neurotrophic Therapy for ALS/MND
Dubowsky, M., Shepheard, S. R. & Rogers, M. L., 2023, Handbook of Neurotoxicity, Second Edition. Kostrzewa, R. M. (ed.). 2nd ed. Cham, Switzerland: Springer International Publishing, Vol. 3. p. 1893-1929 37 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Open Access
Prizes
Activities
- 4 Oral presentation
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ProNGF mediates death of Natural Killer cells through the p75NTR-sortilin complex
Rogers, M.-L. (Speaker), Bailey, S. (Speaker), Matusica, D. (Speaker), Nicholson, I. (Speaker), Pagadala, P. (Speaker), Neet, K. (Speaker), Zola, H. (Speaker), Macardle, P. J. (Speaker) & Rush, R. (Speaker)
14 Jun 2010 → 17 Jun 2010Activity: Talk or presentation types › Oral presentation
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NGF and BDNF have different sub-cellular fates via p75NTR trafficking
Matusica, D. (Speaker), Rogers, M.-L. (Speaker) & Rush, R. (Speaker)
7 Jul 2007Activity: Talk or presentation types › Oral presentation
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Functional Monoclonal Antibodies that Bind to Mouse p75 Neurotrophin Receptor
Rogers, M.-L. (Speaker), Matusica, D. (Speaker), Abebe, D. (Speaker), Macardle, P. J. (Speaker) & Rush, R. (Speaker)
31 Jan 2006 → 3 Feb 2006Activity: Talk or presentation types › Oral presentation
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Ligand-induced internalization of p75NTR and associated receptors in NSC-34 motoneuron-like cells
Matusica, D. (Speaker), Rogers, M.-L. (Speaker) & Rush, R. (Speaker)
8 Jun 2006 → 11 Jun 2006Activity: Talk or presentation types › Oral presentation