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1989 …2024

Research activity per year

Personal profile

Research Biography

Michael Michael is a Hospital Medical Scientist who leads the Gene Expression Laboratory at Flinders Centre for Innovation in Cancer. After helping to establish one of Australia's first biotechnology companies, Michael moved to Flinders, in 1998, in the pursuit of biomarkers for colorectal cancer. He pioneered global profiling of microRNAs to identify associations with disease, particularly solid tumours. His interests have broadened to investigate the involvement of epigenetics and non-coding RNAs in various aspects of human development and disease. However, the focus of his lab is still to deliver diagnostic tests that will inform clinical decision-making and to identify drug targets for novel therapeutics. Michael contributes to community and regulatory bodies, including the Gene Technology Technical Advisory Committee of the Office of the Gene Technology Regulator.

Supervised Students Successes

  • Sep 2018 Ayla Orang - ASBMB Student Poster Prize; ComBio2018
  • Aug 2018 Saira Ali - 3 Minute Thesis competition; runner-up & People's choice award Flinders University
  • Sep 2017 Ayla Orang - 3 Minute Thesis competition; winner Flinders University

Completed Supervisions

Principal Supervisions:
  • Colorectal cancer, microRNAs, diet, epigenetics (1)
Associate Supervisions:
  • Epigenetics, Gene expression, Leukemia (1)
  • microRNA biosynthesis, hypoxia, cancer cell biology (1)
  • Prostate cancer, transcriptional regulation, androgen response (1)
  • Radiation research, DNA methylation, genomic stability (1)
  • Retinopathy, gene expression, microRNAs, hyperoxia (1)
  • Upper GI cancers, microRNAs, biomarkers (1)


  • Registered

Research Areas

  • Medical biosciences

Supervisory Interests

  • Gastrointestinal cancers, altered gene expression
  • MicroRNA-regulated gene expression
  • Epigenetics and dietary regulation of gene expression
  • Exosome-mediated intercellular signalling


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