Natalie’s research program aims to advance the understanding, prediction, and prevention of externalising psychopathology (e.g., aggression, impulsivity) and callous-unemotional (CU) traits (i.e., shallow affect and empathy) in young people. Specifically, her research aims to: (a) elucidate early etiological profiles contributing to the emergence of externalising psychopathology and CU traits, including prenatal experiences, parenting behaviours, and emotional processing; (b) understand specific biological systems (focusing on neuroendocrine, inflammatory, and psychophysiological indices) related to the development and maintenance of externalising psychopathology and CU traits; (c) apply diverse methodologies (e.g., micro [intensive real-time] and macro [long-term panel] longitudinal methods) and analytic approaches (e.g., dynamic modeling, integrative data techniques) to better characterise the persistence of externalising psychopathology and CU traits; and (d) mobilise knowledge from this developmental work to inform and evaluate preventive interventions targeting externalising psychopathology and CU traits.