Research output per year
Research output per year
Personal profile
Research Biography
Dr Nuy Chau completed a Bachelor of Science (First Class Honours) in Pharmacology in 2010 and subsequently a PhD in Pharmacology in 2019 from Flinders University of South Australia. Her PhD thesis investigated the enzymology of human drug and chemical glucosidation, a less well known metabolic pathway for drugs in humans. Nuy is currently based in the Drug Metabolism Laboratory with Professor John Miners and Dr Pramod Nair investigating the structure-function of drug metabolising enzymes (UGTs and CYPs), using a combination of computational and experimental approaches to understand the mechanisms of ligand (substrate/cofactor) recognition and binding.
Education/Academic qualification
PhD, Flinders University
Award Date: 26 Sep 2019
Bachelor of Science (Honours), Flinders University
Award Date: 23 Apr 2010
Bachelor, Flinders University
Award Date: 17 Apr 2008
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Research output
- 321 Citations
- 7 h-Index
- 9 Article
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Drug and chemical glucosidation by control supersomes and membranes from spodoptera frugiperda (sf) 9 cells: Implications for the apparent glucuronidation of xenobiotics by UDP-glucuronosyltransferase 1A5
Chau, N., Kaya, L., Lewis, B. C., Mackenzie, P. I. & Miners, J. O., 1 Mar 2019, In: Drug Metabolism and Disposition. 47, 3, p. 271-278 8 p.Research output: Contribution to journal › Article › peer-review
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Inhibition of human UDP-glucuronosyltransferase (UGT) enzymes by kinase inhibitors: Effects of dabrafenib, ibrutinib, nintedanib, trametinib and BIBF 1202
Korprasertthaworn, P., Chau, N., Nair, P. C., Rowland, A. & Miners, J. O., Nov 2019, In: Biochemical Pharmacology. 169, 10 p., 113616.Research output: Contribution to journal › Article › peer-review
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Inhibition of human UDP-glucuronosyltransferase enzymes by lapatinib, pazopanib, regorafenib and sorafenib: Implications for hyperbilirubinemia
Miners, J., Chau, N., Rowland, A., Burns, K., McKinnon, R., Mackenzie, P., Tucker, G., Knights, K. & Kichenadasse, G., 1 Apr 2017, In: Biochemical Pharmacology. 129, p. 85-95 11 p.Research output: Contribution to journal › Article › peer-review
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Scaling factors for the in vitro–in vivo extrapolation (IV–IVE) of renal drug and xenobiotic glucuronidation clearance
Knights, K., Spencer, S., Fallon, J., Chau, N., Smith, P. & Miners, J., 2016, (E-pub ahead of print) In: British Journal of Clinical Pharmacology. 81, 6, p. 1153-1164 12 p.Research output: Contribution to journal › Article › peer-review
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Inhibition of Human UDP-Glucuronosyltransferase Enzymes by Canagliflozin and Dapagliflozin: Implications for Drug-Drug Interactions
Pattanawongsa, A., Chau, N., Rowland, A. & Miners, J., 1 Oct 2015, In: Drug Metabolism and Disposition. 43, 10, p. 1468-1476 9 p.Research output: Contribution to journal › Article › peer-review