Dr Pramod Nair

  • 1031 Citations
  • 12 h-Index
20062020

Research output per year

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Personal profile

Research Biography

Dr Nair obtained a Bachelor of Pharmaceutical Sciences with Distinction at the University of Mumbai (Bombay College of Pharmacy) India, in 2005. He completed his Masters of Science (Pharm.) at National Institute of Pharmaceutical Education and Research (NIPER) India, where he also worked as a Junior Research Fellow. He received the Australian government funded Endeavour IPRS fellowship in 2009 and undertook Phd studies with Professor Alan Mark at the School of Chemistry & Molecular Biosciences, The University of Queensland. In 2013 he joined the Department of Clinical Pharmacology as a Postdoctoral researcher in the laboratory of Professor John Miners and Professor Ross McKinnon.

Research Interests

Pramod's research focuses on combining diverse computational and experimental approaches for understanding the mechanisms of ligand recognition by P450's and UGT proteins. The main aim of his research is to support the rational design of drugs, particularly, in relation to drug lead optimization, drug metabolism, and drug-drug interaction potential.

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Research Output

Binding of clozapine to the GABAB receptor: clinical and structural insights

Nair, P. C., McKinnon, R. A., Miners, J. O. & Bastiampillai, T., 1 Sep 2020, In : MOLECULAR PSYCHIATRY. 25, 9, p. 1910-1919 10 p.

Research output: Contribution to journalArticle

  • 1 Citation (Scopus)

    Slow tight binding inhibition of CYP17A1 by abiraterone redefines its kinetic selectivity and dosing regimen

    Cheong, E. J. Y., Nair, P. C., Neo, R. W. Y., Tu, H. T., Lin, F., Chiong, E., Esuvaranathan, K., Fan, H., Szmulewitz, R., Peer, C. J., Figg, W. D., Chai, C. L. L., Miners, J. O. & Chan, E. C. Y., 1 Sep 2020, In : The Journal of pharmacology and experimental therapeutics. 374, 3, p. 438-451 14 p.

    Research output: Contribution to journalArticle

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  • 2 Citations (Scopus)

    Inhibition of Hepatic CYP2D6 by the Active N-Oxide Metabolite of Sorafenib

    Murray, M., Gillani, T. B., Rawling, T. & Nair, P. C., 1 Nov 2019, In : AAPS Journal. 21, 6, 107 (2019).

    Research output: Contribution to journalArticle