• 910 Citations
  • 16 h-Index
20002019

Research output per year

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Personal profile

Research Biography

Dr Ormsby currently manages the South Australian Neurological Tumour Bank located at Flinders University having established specimen and clinical data collection at the major hospitals in Adelaide. She has extensive experience organizing recruitment of participants, coordinating with neurosurgeons, clinicians and theatre staff to obtain and process surgically removed neurological tumour tissue, normal brain tissue and cerebral spinal fluid as well as sourcing and collating associated patient clinical data.

 

Dr Ormsby obtained her PhD in 2005 at Flinders University during which she spent time at the Hans Knoll Institute, Germany and the University of Helsinki, Finland. Her subsequent research identified the functional implications of a common genetic variant in the complement protein Factor H that increases the risks of age-related macular degeneration (Ormsby et al 2008).

 

Between 2007-2014 she worked as a Research Fellow in the Flinders Centre for Innovation in Cancer in the areas of cancer and radiation biology, studying the effects of ionizing radiation on DNA damage (Ormsby et al 2016), mutation, epigenetic changes (Newman et al 2014a; 2014b), as well as the effect of radioprotectors on modulating these responses (Ormsby et al 2014).

Research Expertise

Dr Ormsby currently manages the South Australian Neurological Tumour Bank located at Flinders University having established specimen and clinical data collection at the major hospitals in Adelaide. She has extensive experience organizing recruitment of participants, coordinating with neurosurgeons, clinicians and theatre staff to obtain and process surgically removed neurological tumour tissue, normal brain tissue and cerebral spinal fluid as well as sourcing and collating associated patient clinical data.

Research Interests

  • Brain and spinal cord tissue processing and preservation
  • Molecular biology
  • Proteomics

Education/Academic qualification

Bachelor of Science (Honours), University of Adelaide

Award Date: 2 May 2006

PhD, Flinders University

Award Date: 16 Dec 2005

Bachelor of Science, University of Adelaide

Award Date: 2 May 1995

External positions

Research Assistant, Nuclear Fuel Cycle Royal Commission

30 Jun 201530 Oct 2015

Keywords

  • RC0254 Neoplasms. Tumors. Oncology (including Cancer)
  • Tumors
  • RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
  • Neurological

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Research Output

  • 910 Citations
  • 16 h-Index
  • 27 Article
  • 3 Meeting Abstract
  • 1 Paper

DMAPT is an Effective Radioprotector from Long-Term Radiation-Induced Damage to Normal Mouse Tissues In Vivo

Morel, K. L., Ormsby, R. J., Klebe, S., Sweeney, C. J. & Sykes, P. J., 1 Aug 2019, In : Radiation Research. 192, 2, p. 231-239 9 p.

Research output: Contribution to journalArticle

  • 3 Citations (Scopus)

    The combination of metformin and valproic acid has a greater anti-tumoral effect on prostate cancer growth in vivo than either drug alone

    Tran, L. N. K., Kichenadasse, G., Morel, K. L., Lavranos, T. C., Klebe, S., Lower, K. M., Ormsby, R. J., Elliot, D. J. & Sykes, P. J., Jan 2019, In : IN VIVO. 33, 1, p. 99-108 10 p.

    Research output: Contribution to journalArticle

  • 1 Citation (Scopus)

    Chronic low dose ethanol induces an aggressive metastatic phenotype in TRAMP mice, which is counteracted by parthenolide

    Morel, K., Ormsby, R., Solly, E., Tran, L. N. K., Sweeney, C., Klebe, S., Cordes, N. & Sykes, P., 23 Jun 2018, In : CLINICAL & EXPERIMENTAL METASTASIS. 35, 7, p. 649-661 13 p.

    Research output: Contribution to journalArticle

  • 1 Citation (Scopus)

    Combination of metformin and sodium valproate for prostate cancer: a rapid approach from bench to clinical trial

    Tran, L., Kichenadasse, G., Ormsby, R., Morel, K., Butler, L., Centenera, M. & Sykes, P., 2017, In : Journal of Urology. 197, 4S, p. e1108-e1109 2 p.

    Research output: Contribution to journalMeeting Abstract

    Parthenolide selectively sensitizes prostate tumor tissue to radiotherapy while protecting healthy tissues in vivo

    Morel, K., Ormsby, R., Bezak, E., Sweeney, C. & Sykes, P., 2017, In : Radiation Research. 187, 5, p. 501-512 12 p.

    Research output: Contribution to journalArticle

  • 19 Citations (Scopus)