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1988 …2021

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Personal profile

Research Biography

Chief Medical Scientist: Molecular Pathology, SA Pathology, Flinders Medical Centre (2011-)
Senior Medical Scientist: Haematology and Genetic Pathology, Flinders Medical Centre (2003-2011)
Senior Lecturer: School of Medicine, Flinders University of South Australia. (2006-)

Research Interests

Assay for genomic instability in inherited breast cancer - improving classification of genetic variants and increasing access to effective genetic screening. The effects of low-dose ionizing radiation on cells carrying genetic mutations implicated in genomic instability (with specific reference to diagnostic and therapeutic radiation regimes in inherited breast cancer).

Development of a novel assay for ATM function in B-cell chronic lymphocytic leukaemia (CLL): improving prognostic classification and enabling better therapeutic selection for high-risk CLL.


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Collaborations and top research areas from the last five years

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  • Population-based estimates of breast cancer risk for carriers of pathogenic variants identified by gene-panel testing

    Southey, M. C., Dowty, J. G., Riaz, M., Steen, J. A., Renault, A. L., Tucker, K., Kirk, J., James, P., Winship, I., Pachter, N., Poplawski, N., Grist, S., Park, D. J., Pope, B. J., Mahmood, K., Hammet, F., Mahmoodi, M., Tsimiklis, H., Theys, D., Rewse, A., & 12 othersWillis, A., Morrow, A., Speechly, C., Harris, R., Sebra, R., Schadt, E., Lacaze, P., McNeil, J. J., Giles, G. G., Milne, R. L., Hopper, J. L. & Nguyen-Dumont, T., Dec 2021, In: npj Breast Cancer. 7, 1, 7 p., 153.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Citations (Scopus)
    4 Downloads (Pure)
  • HAT-PCR is More Sensitive Than Flow for Quantifying MRD in Chronic Lymphocytic Leukemia

    Morley, A., Latham, S., Hughes, E., Kuss, B., Grist, S., Hall, R., Tam, C., Carney, D., Cull, G., Mulligan, S., Bailey, S., Sartor, M. & Gottlieb, D., Jun 2019, In: HemaSphere. 3, S1, p. 146-146 1 p., PF388.

    Research output: Contribution to journalMeeting Abstractpeer-review

    Open Access
  • RAD51B in familial breast cancer

    Pelttari, L. M., Khan, S., Vuorela, M., Kiiski, J. I., Vilske, S., Nevanlinna, V., Ranta, S., Schleutker, J., Winqvist, R., Kallioniemi, A., Dörk, T., Bogdanova, N. V., Figueroa, J., Pharoah, P. D. P., Schmidt, M. K., Dunning, A. M., García-Closas, M., Bolla, M. K., Dennis, J., Michailidou, K., & 84 othersWang, Q., Hopper, J. L., Southey, M. C., Rosenberg, E. H., Fasching, P. A., Beckmann, M. W., Peto, J., dos-Santos-Silva, I., Sawyer, E. J., Tomlinson, I., Burwinkel, B., Surowy, H., Guénel, P., Truong, T., Bojesen, S. E., Nordestgaard, B. G., Benitez, J., González-Neira, A., Neuhausen, S. L., Anton-Culver, H., Brenner, H., Arndt, V., Meindl, A., Schmutzler, R. K., Brauch, H., Brüning, T., Lindblom, A., Margolin, S., Mannermaa, A., Hartikainen, J. M., Chenevix-Trench, G., kConFab/AOCS Investigators, Van Dyck, L., Janssen, H., Chang-Claude, J., Rudolph, A., Radice, P., Peterlongo, P., Hallberg, E., Olson, J. E., Giles, G. G., Milne, R. L., Haiman, C. A., Schumacher, F., Simard, J., Dumont, M., Kristensen, V., Borresen-Dale, A. L., Zheng, W., Beeghly-Fadiel, A., Grip, M., Andrulis, I. L., Glendon, G., Devilee, P., Seynaeve, C., Hooning, M. J., Collée, M., Cox, A., Cross, S. S., Shah, M., Luben, R. N., Hamann, U., Torres, D., Jakubowska, A., Lubinski, J., Couch, F. J., Yannoukakos, D., Orr, N., Swerdlow, A., Darabi, H., Li, J., Czene, K., Hall, P., Easton, D. F., Mattson, J., Blomqvist, C., Aittomäki, K., Nevanlinna, H., Firgaira, F., Grist, S., Haan, E., Seshadri, R., Sykes, P. & Henderson, D., 5 May 2016, In: PLoS One. 11, 5, 18 p., e0153788.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    19 Citations (Scopus)
    7 Downloads (Pure)
  • Annexin A1 expression in a pooled breast cancer series: Association with tumor subtypes and prognosis

    Sobral-Leite, M., Wesseling, J., Smit, V. T. H. B. M., Nevanlinna, H., van Miltenburg, M. H., Sanders, J., Hofland, I., Blows, F. M., Coulson, P., Patrycja, G., Schellens, J. H. M., Fagerholm, R., Heikkilä, P., Aittomäki, K., Blomqvist, C., Provenzano, E., Ali, H. R., Figueroa, J., Sherman, M., Lissowska, J., & 27 othersMannermaa, A., Kataja, V., Kosma, V. M., Hartikainen, J. M., Phillips, K., kConFab/AOCS Investigators, Couch, F. J., Olson, J. E., Vachon, C., Visscher, D., Brenner, H., Butterbach, K., Arndt, V., Holleczek, B., Hooning, M. J., Hollestelle, A., Martens, J. W. M., van Deurzen, C. H. M., van de Water, B., Broeks, A., Chang-Claude, J., Chenevix-Trench, G., Easton, D. F., Pharoah, P. D. P., García-Closas, M., de Graauw, M. & Schmidt, M. K., 2 Jul 2015, In: BMC Medicine. 13, 1, 11 p., 156.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    44 Citations (Scopus)
    11 Downloads (Pure)
  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Michailidou, K., Beesley, J., Lindstrom, S., Canisius, S., Dennis, J., Lush, M., Maranian, M., Bolla, M., Wang, Q., Shah, M. & Grist, S., 28 Apr 2015, In: Nature Genetics. 47, 4, p. 373-380 8 p.

    Research output: Contribution to journalArticlepeer-review

    409 Citations (Scopus)