Emeritus Professor Terry Nicholas

Research output

Research output per year 1974 1974 1978 1981 1982 1983 1989 1990 1993 1994 1997 1998 1999 2001 2002

• 68 Article
• 1 Short survey
• 1 Review article

Research output per year

Research output per year

Search results

• 2002

  Endotoxin induces respiratory failure and increases surfactant turnover and respiration independent of alveolocapillary injury in rats

  Davidson, K., Bersten, A., Barr, H., Dowling, K., Nicholas, T. & Doyle, I., 2002, In: American Journal of Respiratory and Critical Care Medicine. 165, 11, p. 1516-1525 10 p.

  Research output: Contribution to journal › Article › peer-review

  34 Citations (Scopus)
• 2001

  Elevated plasma surfactant protein-B predicts development of acute respiratory distress syndrome in patients with acute respiratory failure

  Bersten, A., Hunt, T., Nicholas, T. & Doyle, I., 2001, In: American Journal of Respiratory and Critical Care Medicine. 164, 4, p. 648-652 5 p.

  Research output: Contribution to journal › Article › peer-review

  58 Citations (Scopus)

• Recruiting problem-based learning (PBL) tutors for a PBL-based curriculum: the Flinders University experience

  Finucane, P., Nichols, F., Gannon, B., Runciman, S., Prideaux, D. & Nicholas, T., 2001, In: Medical Education. 35, p. 56-61 6 p.

  Research output: Contribution to journal › Article › peer-review

  24 Citations (Scopus)

• The new medical curriculum at Flinders University, South Australia: from concept to reality

  Finucane, P., Nicholas, T. & Prideaux, D., 2001, In: Medical Teacher. 23, 1, p. 76-79 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Problem-Based Learning 100%
  • Curricular Reform 100%
  13 Citations (Scopus)
• 2000

  Composition of alveolar surfactant changes with training in humans

  Doyle, I., Morton, S., Crockett, A., Barr, H., Davidson, K., Jones, M., Jones, M. & Nicholas, T., 2000, In: Respirology. 5, 3, p. 211-220 10 p.

  Research output: Contribution to journal › Article › peer-review

  9 Citations (Scopus)

• Lung function, permeability, and surfactant composition in oleic acid-induced acute lung injury in rats

  Davidson, K. G., Bersten, A. D., Barr, H. A., Dowling, K. D., Nicholas, T. E. & Doyle, I. R., 1 Dec 2000, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 279, 6, p. L1091-L1102 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Acute Lung Injury 100%
  • Surfactant 100%
  • Oleic Acid 100%
  • Phospholipid 100%
  • Lung Minute Volume 100%
  73 Citations (Scopus)
• 1999

  Cyclic stretch induces both apoptosis and secretion in rat alveolar type II cells

  Edwards, Y., Sutherland, L., Power, J., Nicholas, T. & Murray, A., 1999, In: FEBS Letters. 448, 1, p. 127-130 4 p.

  Research output: Contribution to journal › Article › peer-review

  69 Citations (Scopus)

• Immunohistochemical localization and characterization of a rat Clara cell 26-kDa protein (CC26) with similarities to glutathione peroxidase and phospholipase A₂

  Power, J. H. T. & Nicholas, T. E., 1999, In: Experimental Lung Research. 25, 5, p. 379-392 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Amino Acids 100%
  • Phospholipase A2 100%
  • Glutathione Peroxidase 100%
  • Clara Cell 100%
  • N-Terminus 66%
  25 Citations (Scopus)

• Measurement of tidal volume by using transthoracic impedance variations in rats

  Davidson, K. G., Bersten, A. D., Nicholas, T. E., Ravenscroft, P. R. & Doyle, I. R., Feb 1999, In: Journal of Applied Physiology. 86, 2, p. 759-766 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Tidal Volume 100%
  • Electrical Impedance 100%
  • Pneumography 33%
  • Pulmonary Edema 16%
  • Adhesive Agent 16%
  15 Citations (Scopus)

• Partitioning lung and plasma proteins: Circulating surfactant proteins as biomarkers of alveolocapillary permeability

  Doyle, I. R., Nicholas, T. E. & Bersten, A. D., 23 Mar 1999, In: Clinical and Experimental Pharmacology and Physiology. 26, 3, p. 185-197 13 p.

  Research output: Contribution to journal › Short survey › peer-review

  • Surfactant Protein 100%
  • Serum Total Protein 100%
  • Surface Active Agent 100%
  • Liquid 14%
  • Blood Plasma 14%
  46 Citations (Scopus)

• Plasma surfactant protein-B is elevated in infants with respiratory syncytial virus-induced bronchiolitis

  Wang, S. Z., Doyle, I. R., Nicholas, T. E. & Forsyth, K. D., 1 Dec 1999, In: Pediatric Research. 46, 6, p. 731-734 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Blood Plasma 100%
  • Human Respiratory Syncytial Virus 100%
  • Bronchiolitis 100%
  • Surfactant Protein B 100%
  • Neutrophil 22%
  9 Citations (Scopus)

• Ultrastructural and protein analysis of surfactant in the Australian lungfish Neoceratodus forsteri: Evidence for conservation of composition for 300 million years

  Power, J. H., Doyle, I. R., Davidson, K. & Nicholas, T. E., Sept 1999, In: Journal of Experimental Biology. 202, 18, p. 2543-2550 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Surfactant 100%
  • Protein Characterization 100%
  • Lungfish 100%
  • Osmium 28%
  • Myelin 20%
  36 Citations (Scopus)
• 1998

  Clearance of clara cell secretory protein 16 (CC16) and surfactant proteins A and B from blood in acute respiratory failure

  Doyle, I. R., Hermans, C., Bernard, A., Nicholas, T. E. & Bersten, A. D., 1 Dec 1998, In: American journal of respiratory and critical care medicine. 158, 5 PART I, p. 1528-1535 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Blood Plasma 100%
  • Clara Cell 100%
  • Surfactant Protein A 100%
  • Secretory Protein 100%
  • Glomerulus Filtration 40%
  52 Citations (Scopus)

• Osmotic stress induces both secretion and apoptosis in rat alveolar type II cells

  Edwards, Y., Sutherland, L., Power, J., Nicholas, T. & Murray, A., 1998, In: American Journal of Physiology-Lung Cellular and Molecular Physiology. 275, 4, p. L670-L678

  Research output: Contribution to journal › Article › peer-review

  41 Citations (Scopus)

• Quantity and structure of surfactant proteins vary among patients with alveolar proteinosis

  Doyle, I. R., Davidson, K. G., Barr, H. A., Nicholas, T. E., Payne, K. & Pfitzner, J., 1998, In: American journal of respiratory and critical care medicine. 157, 2, p. 658-664 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Surfactant Protein 100%
  • Surfactant Protein A 100%
  • Surfactant Protein B 60%
  • Right Lung 40%
  • Left Lung 40%
  53 Citations (Scopus)

• Respiratory mechanics and surfactant in the acute respiratory distress syndrome

  Bersten, A. D., Davidson, K., Nicholas, T. E. & Doyle, I. R., Jun 1998, In: Clinical and Experimental Pharmacology and Physiology. 25, 11, p. 955-963 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Breathing Mechanics 100%
  • Acute Respiratory Distress Syndrome 100%
  • Surfactant 100%
  • Adult Respiratory Distress Syndrome 100%
  • Surface Active Agent 100%
  18 Citations (Scopus)

• Surfactant composition reflects lung overinflation and arterial oxygenation in patients with acute lung injury

  Bersten, A. D., Doyle, I. R., Davidson, K. G., Barr, H. A., Nicholas, T. E. & Kermeen, F., Aug 1998, In: European Respiratory Journal. 12, 2, p. 301-308 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Lung 100%
  • Acute Lung Injury 100%
  • Surfactant 100%
  • Phospholipid 57%
  • Pulmonary Surfactant 50%
  21 Citations (Scopus)
• 1997

  Effect of lowering serum cholesterol on the composition of surfactant in adult rat lung

  Davidson, K. G., Acton, S. M., Barr, H. A. & Nicholas, T. E., Jan 1997, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 272, 1 , p. L106-L114

  Research output: Contribution to journal › Article › peer-review

  • Rat 100%
  • Tidal Volume 100%
  • Myelin 100%
  • Pyrimidine 40%
  • Phospholipid Synthesis 33%
  19 Citations (Scopus)

• Inability of Histamine to Regulate TNF-α Production by Human Alveolar Macrophages

  Roe, J., Finlay-Jones, J. J., Nicholas, T. E., Bowden, J., Morton, S. & Hart, P. H., 1 Jan 1997, In: American Journal of Respiratory Cell and Molecular Biology. 17, 2, p. 218-226 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Alveolar Macrophage 100%
  • Tumor Necrosis Factor Alpha 100%
  • Histamine 100%
  • Macrophage 7%
  • Pulmonary Inflammation 7%
  18 Citations (Scopus)

• Surfactant proteins-A and -B are elevated in plasma of patients with acute respiratory failure

  Doyle, I. R., Bersten, A. D. & Nicholas, T. E., 1 Dec 1997, In: American journal of respiratory and critical care medicine. 156, p. 1217-1229 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Acute Respiratory Failure 100%
  • Surfactant Protein A 100%
  • Surfactant Protein B 100%
  • Blood Plasma 100%
  • Acute Respiratory Distress Syndrome 42%
  128 Citations (Scopus)

• Surfactant replacement therapy in ARDS: White knight or noise in the system?

  Nicholas, T. E., Doyle, I. R. & Bersten, A. D., 1 Jan 1997, In: Thorax. 52, 2, p. 195-197 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Serum Total Protein 100%
  20 Citations (Scopus)
• 1996

  Differential changes in SP-A and disaturated phospholipids in the isolated perfused rat lung and in vivo

  Doyle, I. R., Barr, H. A., Davidson, K. G. & Nicholas, T. E., Sept 1996, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 271, 3, p. L374-L382 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Rat 100%
  • Lung 100%
  • Phospholipid 100%
  • Surfactant 80%
  • Tidal Volume 40%
  5 Citations (Scopus)

• Pulmonary surfactant: no mere paint on the alveolar wall.

  Nicholas, T. E., Dec 1996, In: Respirology. 1, 4, p. 247-257 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Pulmonary Surfactant 100%
  • Surfactant 100%
  • Surface Active Agent 100%
  • Breathing 33%
  • Lung 16%
  21 Citations (Scopus)
• 1995

  Effect of hyperpnea on the cholesterol to disaturated phospholipid ratio in alveolar surfactant of rats

  Orgeig, S., Barr, H. A. & Nicholas, T. E., 1995, In: Experimental Lung Research. 21, 1, p. 157-174 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Phospholipid 100%
  • Pulmonary Surfactant 100%
  • Hyperpnea 100%
  • Tidal Volume 75%
  • Myelin 50%
  37 Citations (Scopus)

• Serum surfactant protein-A levels in patients with acute cardiogenic pulmonary edema and adult respiratory distress syndrome

  Doyle, I. R., Nicholas, T. E. & Bersten, A. D., Jul 1995, In: American journal of respiratory and critical care medicine. 152, 1, p. 307-317 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Lung Edema 100%
  • Adult Respiratory Distress Syndrome 100%
  • Surfactant Protein A 100%
  • Diseases 33%
  • Membrane Damage 33%
  100 Citations (Scopus)
• 1994

  Composition of human pulmonary surfactant varies with exercise and level of fitness

  Doyle, I. R., Jones, M. E., Barr, H. A., Orgeig, S., Crockett, A. J., Mcdonald, C. F. & Nicholas, T. E., Jun 1994, In: American journal of respiratory and critical care medicine. 149, 6, p. 1619-1627 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Pulmonary Surfactant 100%
  • Phospholipid 100%
  • Surfactant Protein A 100%
  • Surfactant 60%
  • Bronchoalveolar Lavage 40%
  61 Citations (Scopus)

• Distribution of surfactant protein A in rat lung.

  Doyle, I. R., Barr, H. & Nicholas, T. E., Oct 1994, In: American Journal of Respiratory Cell and Molecular Biology. 11, 4, p. 405-415 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Surfactant Protein A 100%
  • Phospholipid 66%
  • Protein Electrophoresis 50%
  • Surfactant 44%
  • Myelin 22%
  23 Citations (Scopus)

• Pulmonary-type surfactants in the lungs of terrestrial and aquatic amphibians

  Daniels, C. B., Orgeig, S., Wilsen, J. & Nicholas, T. E., Mar 1994, In: Respiration Physiology. 95, 3, p. 249-258 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Breathing Pattern 100%
  • Hydrostatic Pressure 56%
  • Amphiuma 18%
  • Liquid Crystal 18%
  • Phosphatidylinositol 18%
  28 Citations (Scopus)
• 1993

  Characterization and immunohistochemical localization of the 15 kD protein isolated from rat lung lamellar bodies.

  Power, J. H., Barr, H. A. & Nicholas, T. E., Jan 1993, In: American Journal of Respiratory Cell and Molecular Biology. 8, 1, p. 98-105 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Rat 100%
  • Lavage 20%
  • Myelin 20%
  • Electron Microscope 20%
  • Ultracentrifugation 20%
  4 Citations (Scopus)

• The role of surfactant in the static lung mechanics of the lizard Ctenophorus nuchalis

  Daniels, C. B., Eskandari-Marandi, B. D. & Nicholas, T. E., Oct 1993, In: Respiration Physiology. 94, 1, p. 11-23 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Surfactant 100%
  • Lung 100%
  • Body Temperature 16%
  • Australians 8%
  11 Citations (Scopus)

• Turnover of cholesterol and dipalmitoyl phosphatidylcholine in surfactant of adult rat lung

  Jones, M. E., Barr, H. A. & Nicholas, T. E., 1 Mar 1993, In: Lipids. 28, 3, p. 173-179 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Lung 100%
  • Surfactant 100%
  • Lamellar Body 100%
  • Precursor 57%
  • Pulmonary Surfactant 57%
  10 Citations (Scopus)
• 1992

  Effect of artificial ventilation and anaesthesia on surfactant turnover in rats

  Ward, H. E. & Nicholas, T. E., Jan 1992, In: Respiration Physiology. 87, 1, p. 115-129 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Breathing 100%
  • Artificial Respiration 100%
  • Surfactant 100%
  • Apnea 50%
  • Tidal Volume 50%
  20 Citations (Scopus)
• 1991

  Growth retardation and the development of the respiratory system in fetal sheep

  Rees, S., Ng, J., Dickson, K., Nicholas, T. & Harding, R., Jul 1991, In: Early Human Development. 26, 1, p. 13-27 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Growth Retardation 100%
  • Phospholipid 66%
  • Intrauterine Growth Retardation 33%
  • Pulmonary Surfactant 33%
  34 Citations (Scopus)
• 1990

  Body temperature alters the lipid composition of pulmonary surfactant in the Lizard ctenophorus nuchalis

  Daniels, C. B., Barr, H. A., Power, J. H. T. & Nicholas, T. E., 1990, In: Experimental Lung Research. 16, 5, p. 435-449 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Body Temperature 100%
  • Pulmonary Surfactant 100%
  • Cholesterol 100%
  • Lipid Composition 100%
  • Phospholipids 75%
  63 Citations (Scopus)

• Effect of pattern of breathing on subfractions of surfactant in tissue and alveolar compartments of the adult rat lung.

  Nicholas, T. E., Power, J. H. & Barr, H. A., Sept 1990, In: American Journal of Respiratory Cell and Molecular Biology. 3, 3, p. 251-258 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Rat 100%
  • Surfactant 100%
  • Lung 100%
  • Phospholipid 100%
  • Tidal Volume 100%
  22 Citations (Scopus)

• Uptake of instilled radiolabeled lamellar bodies from alveolar compartment of the rat

  Nicholas, T. E., Barr, H. A., Power, J. H. T. & Jones, M. E., 1 Oct 1990, In: American Journal of Physiology-Lung Cellular and Molecular Physiology. 259, 4 , p. L238-L246 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Choline 100%
  • Reuptake 57%
  • Carbon 14 28%
  • Hyperpnea 28%
  • Adrenergic Receptor 14%
  7 Citations (Scopus)
• 1989

  A comparison of the surfactant associated lipids derived from reptilian and mammalian lungs

  Daniels, C. B., Barr, H. A. & Nicholas, T. E., Mar 1989, In: Respiration Physiology. 75, 3, p. 335-347 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Unsaturated Fatty Acid 100%
  • Cholesterol Ester 49%
  • Palmitic Acid 49%
  • Dipalmitoylphosphatidylcholine 49%
  • Phosphatidylglycerol 49%
  17 Citations (Scopus)

• Effect of hyperpnea on enzymes of the CDPcholine path for phosphatidylcholine synthesis in rat lung

  Barr, H. A., Nicholas, T. E. & Power, J. H. T., 1 Aug 1989, In: Lipids. 24, 8, p. 709-714 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Enzyme 100%
  • Phosphorylcholine 100%
  • Lecithin 100%
  • Tidal Volume 100%
  • Choline 50%
  7 Citations (Scopus)

• The processing of exogenous cholesterol in the alveolar compartment of the rat lung

  Hayball, P. J. & Nicholas, T. E., 1 Nov 1989, In: Lipids. 24, 11, p. 957-961 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Lung 100%
  • Cholesterol Ester 100%
  • Rat 100%
  • Macrophage 100%
  • Surfactant 100%
  8 Citations (Scopus)
• 1988

  Control of alveolar surfactant in rats at rest and during prolonged hyperpnoea: pharmacological evidence for two tissue pools of surfactant

  Barr, H. A., Nicholas, T. E. & Power, J. H. T., Mar 1988, In: British Journal of Pharmacology. 93, 3, p. 473-482 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Labetalol 100%
  8 Citations (Scopus)

• Surfactant-associated 15-and 35-kda proteins are concentrated in different organelles in rat lung tissue

  Power, J. H. T., Barr, H. A. & Nicholas, T. E., 1 Jan 1988, In: Experimental Lung Research. 14, 2, p. 209-224 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Surfactant 100%
  • Phospholipid 66%
  • Sucrose 33%
  • Centrifugation 33%
  • Enzyme 33%
  15 Citations (Scopus)
• 1987

  Changes in surfactant pools after a physiological increase in alveolar surfactant

  Power, J. H. T., Barr, H. A., Jones, M. E. & Nicholas, T. E., 1987, In: Journal of Applied Physiology. 63, 5, p. 1902-1911 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Surfactant 100%
  • Pulmonary Surfactant 100%
  • Rat 100%
  • Tidal Volume 66%
  • Myelin 66%
  20 Citations (Scopus)

• Identification of precursor-product relationships in kinetic studies involving radiolabeled tracer molecules

  Jones, M. E., Power, J. H. T., Barr, H. A. & Nicholas, T. E., Nov 1987, In: International Journal of Bio-Medical Computing. 21, 3-4, p. 237-251 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Rat 100%
  • Lung 100%
  • Least Square 100%
  • Phospholipid 100%
  • Precursor 100%
  1 Citation (Scopus)
• 1986

  Analysis of pulmonary phospholipid compartments in the unanesthetized rat during prolonged periods of hyperpnea

  Power, J. H. T., Jones, M. E., Barr, H. A. & Nicholas, T. E., 1986, In: Experimental Lung Research. 11, 2, p. 105-128 24 p.

  Research output: Contribution to journal › Article › peer-review

  • Precursor 100%
  • Phospholipid 100%
  • Myelin 100%
  • Rat 100%
  • Lung 100%
  28 Citations (Scopus)

• Determination of time constants in kinetic studies involving radiolabeled tracer molecules

  Jones, M. E., Nicholas, T. E., Power, J. H. T. & Barr, H. A., Nov 1986, In: International Journal of Bio-Medical Computing. 19, 3-4, p. 235-247 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Constant Time 100%
  • Tracer 100%
  • Error Pattern 25%
  2 Citations (Scopus)
• 1985

  The role of the autonomic nervous system in surfactant(s) release in rats

  Nicholas, T. E., Barr, H. A. & Power, J. H. T., 1 Jan 1985, In: Federation Proceedings. 44, 6, p. No. 8638

  Research output: Contribution to journal › Article › peer-review

  • Autonomic Nervous System 100%
  • Salbutamol 100%
  • Surfactant 100%
  • Pilocarpine 50%
  • Phospholipid 25%
• 1984

  Alveolar Type I and Type II Cells

  Ward, H. E. & Nicholas, T. E., Oct 1984, In: Australian and New Zealand Journal of Medicine. 14, S3, p. 731-734 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Gas Exchange 100%
  • Alveolar Type II Cells 50%
  • Pulmonary Surfactant 50%
  • Progenitor Cell 50%
  56 Citations (Scopus)

• Limitations of Zilversmit approach to analysis of precursor-product relationships

  Jones, M. E. & Nicholas, T. E., 1 Sept 1984, In: Journal of Applied Physiology. 57, 3, p. 892-898 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Phospholipid 100%
  • Collinearity 100%
  • Leporidae 100%
  • Prematurity 33%
  6 Citations (Scopus)
• 1983

  High frequency oscillations via the pleural surface: An alternative mode of ventilation?

  Ward, H. E., Power, J. H. T. & Nicholas, T. E., Feb 1983, In: Journal of Applied Physiology. 54, 2, p. 427-433 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxygen Consumption 100%
  • High Frequency Oscillations 100%
  • Continuous Positive Airway Pressure 75%
  • Tidal Volume 75%
  • Lung 25%
  6 Citations (Scopus)

• The release of surfactant in rat lung by brief periods of hyperventilation

  Nicholas, T. E. & Barr, H. A., Apr 1983, In: Respiration Physiology. 52, 1, p. 69-83 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Lung 100%
  • Hyperventilation 100%
  • Surfactant 100%
  • Tidal Volume 100%
  • In Vivo 50%
  74 Citations (Scopus)