Personal profile
Research Biography
Tom Gordon is a graduate of the University of Adelaide and Professor and Head of the Department of Immunology at Flinders University and the Flinders Medical Centre site of SA Pathology. He is a clinical immunologist, rheumatologist and immunopathologist with an interest in systemic autoimmune diseases, particularly lupus and Sjögren’s syndrome. He worked as a post-doctoral fellow at the Scripps Clinic in San Diego, California and was a Greenberg fellow at the Oklahoma Medical Research Foundation. He is an International Member of the American College of Rheumatology and past member of the ANA Committee of the International Union of Immunological Societies. He has more than 30 years of funding from the NH & MRC for his translational research program on autoimmune diseases and has pioneered mass spectrometric sequencing of human autoantibody repertoires. He has published extensively in the Journal of Immunology, PNAS, Journal of Experimental Medicine, Journal of Clinical Investigation, Lancet, Arthritis and Rheumatism and Gastroenterology. He was awarded the Parr Prize in Rheumatology in 1995 and the International Ethel Baxter award of the American College of Rheumatology in 1998 and 1999 for research on autoantibodies in Sjögren’s syndrome.
Completed Supervisions
- A functional autoantibody in narcolepsy (1)
- B Cell apotopes of the 60-kDa Ro/SSA and La/SSB autoantigens (1)
- Characterisation of antibodies in Sjogren's Syndrome (1)
- Characterization of autoantibodies inhibiting parasympathetic neurotransmission (1)
- functional autoantibodies in type 1 diabetes (1)
- Molecular characterisation of human autoantibodies (1)
- The role of apoptosis and autoantibodies in congenital heart block (1)
- Apoptosis as a source of Antigenic Drive in Systemic Autoimmunity (1)
- Characterisation of tumour-associated HLA Class I genetic and epigenetic gene alterations (1)
- Hierarchical self-tolerance to the LA (SS-B) Nuclear Autoantigen (1)
- Immunological tolerance and autoimmunity to the ubiquitous autoantigens LA and RO (1)
- MHC Class I Antigen Processing and Presentation (1)
Supervision
- Registered
Research Areas
- Medical biosciences
Supervisory Interests
- Systemic autoimmune diseases
- Autoantibodies
- Immunochemistry
- Proteomic analysis of antibodies
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Adenoviral Inciting Antigen and Somatic Hypermutation in VITT
Wang, J. J., Schönborn, L., Warkentin, T. E., Müller, L., Thiele, T., Ulm, L., Völker, U., Ameling, S., Franzenburg, S., Kaderali, L., Tzvetkova, A., Colella, A., Chataway, T., Tan, C. W., Armour, B., Troelnikov, A., Rutten, L., McCluskey, J., Zahn, R. & Gordon, T. & 1 others, , 12 Feb 2026, In: The New England journal of medicine. 394, 7, p. 669-683 15 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Structural Mass-Spectrometric Description of Immune Complexes in Vaccine-Induced Immune Thrombocytopenia and Thrombosis
Troelnikov, A., Ellis, S., Collela, A., Schönborn, L., Greinacher, A., Gordon, T. P., Pukala, T. L., Chataway, T. & Wang, J. J., 8 Apr 2026, In: Journal of the American Chemical Society. 148, 13, p. 13610-13618 9 p.Research output: Contribution to journal › Article › peer-review
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Anti-PF4 mediated thrombocytopenia and thrombosis associated with acute cytomegalovirus infection displays both HIT-like and VITT-like characteristics
Nicolson, P. L. R., Montague, S. J., Buka, R. J., Calvert, A., Sheppard, J. A. I., Zhang, Y., Wang, J. J., Sharman, J., Hassan, E., Harrison, J., Lawrence, E., El-Dalil, P., Parekh, D., Osman, H., Gordon, T. P., Nazy, I., Warkentin, T. E. & Lester, W. A., Jun 2025, In: British Journal of Haematology. 206, 6, p. 1737-1742 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)13 Downloads (Pure) -
A triad of somatic mutagenesis converges in self-reactive B cells to cause a virus-induced autoimmune disease
Young, C., Singh, M., Jackson, K. J. L., Field, M. A., Peters, T. J., Angioletti-Uberti, S., Frenkel, D., Ravishankar, S., Gupta, M., Wang, J. J., Agapiou, D., Faulks, M. L., Al-Eryani, G., Luciani, F., Gordon, T. P., Reed, J. H., Danta, M., Carr, A., Kelleher, A. D. & Dore, G. J. & 5 others, , 11 Feb 2025, In: Immunity. 58, 2, p. 412-430.e10 29 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)32 Downloads (Pure) -
Clinical correlations of serum anti-dsDNA immunoglobulin subfamilies in patients with systemic lupus erythematosus (SLE)
Wang, J. J., Lin, M. W., Suan, D., Beroukas, D., Gordon, T. P. & Lee, A. Y. S., 2025, In: Autoimmunity. 58, 1, 5 p., 2441992.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)55 Downloads (Pure)
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VITT related antibody and hematology work
Wang, J. J. (Chief Investigator (Project Lead)), Gordon, T. (Chief Investigator), Greinacher, A. (Chief Investigator) & Schönborn, L. (Chief Investigator)
11/08/25 → 31/07/27
Project: Research
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Molecular analysis of pathogenic rheumatoid factor repertoires in patients with primary Sjögren’s syndrome
Wang, J. J. (Chief Investigator (Project Lead)), Thurlings, R. (Chief Investigator), Chataway, T. (Associate Investigator) & Gordon, T. (Chief Investigator)
31/01/22 → 31/12/22
Project: Research
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