Developing Next-Generation Eutectic Gels (Egels) for On-Demand Front-Line Wound Healing and Infection Control

Our RMIT research collaborator has been awarded ($499, 398) IG240100083 through AEA Ignite program. As one of the Investigator, the Flinders University also requires to be listed as part of the contract agreement.

This project aims to advance our next-generation antimicrobial wound treatment gel technology beyond the laboratory. Wound infections can be fatal and yet current treatments are often toxic, ineffective, or require specialized facilities. Our gel, loaded with antimicrobial nanoparticles, exhibits broad activity against a spectrum of clinically-relevant pathogens and provides controlled delivery of antimicrobial compounds and healing factors. This advanced material has numerous applications, but here we will focus on its use in medical science. We will progress our technology from TRL 3 to TRL 5 using in vitro screening and a murine wound infection model to build a preclinical dataset for a Phase 1 human trial.