Discovery of Natural Inhibitors Targeting Cell Wall Biosynthesis and Remodelling in Rhizopus oryzae for Potential Antifungal Therapy

This project aims to identify natural compounds that inhibit cell wall biosynthesis and remodelling pathways in Rhizopus oryzae, a major human fungal pathogen responsible for fatal disease called mucormycosis. By targeting enzymes essential for growth and virulence, the team will discover novel antifungal candidates, paving the way for next-generation therapies to combat invasive fungal infections and address rising antifungal resistance.