A biclonal case of chronic lymphocytic leukaemia with discordant mutational status of the immunoglobulin heavy chain variable region and bimodal CD49d expression

Anya K. Hotinski,; Oliver G. Best; Lauren A. Thurgood,; Karen M. Lower; Bryone J. Kuss

doi:10.1111/bjh.17257

A biclonal case of chronic lymphocytic leukaemia with discordant mutational status of the immunoglobulin heavy chain variable region and bimodal CD49d expression

Anya K. Hotinski,, Oliver G. Best, Lauren A. Thurgood,, Karen M. Lower, Bryone J. Kuss

College of Medicine and Public Health

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

An 87-year-old man with multiple medical comorbidities presented to the haematology clinic in April of 2013 with a six-month history of anorexia, weight loss, progressive anaemia and lymphocytosis. On examination, splenomegaly and small volume widespread lymphadenopathy was observed. The initial blood results showed...

Original language	English
Pages (from-to)	e77-e81
Number of pages	4
Journal	British Journal of Haematology
Volume	192
Issue number	3
Early online date	5 Dec 2020
DOIs	https://doi.org/10.1111/bjh.17257
Publication status	Published - Feb 2021

Keywords

CLL
clonal architecture
IGHV
trisomy 12
whole-exome sequencing

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abstract = "An 87-year-old man with multiple medical comorbidities presented to the haematology clinic in April of 2013 with a six-month history of anorexia, weight loss, progressive anaemia and lymphocytosis. On examination, splenomegaly and small volume widespread lymphadenopathy was observed. The initial blood results showed... ",

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AU - Lower, Karen M.

AU - Kuss, Bryone J.

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KW - whole-exome sequencing

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A biclonal case of chronic lymphocytic leukaemia with discordant mutational status of the immunoglobulin heavy chain variable region and bimodal CD49d expression

Abstract

Keywords

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