A CCD-based high resolution CT system for analysis of trabecular bone tissue

A. Pasini, F. Baruffaldi, M. Bettuzzi, R. Brancaccio, F. Casali, S. Cornacchia, N. Lanconelli, M. P. Morigi, E. Di Nicola, S. Pani, E. Perilli, D. Romani, A. Rossi

Research output: Contribution to journalConference articlepeer-review

2 Citations (Scopus)


This paper illustrates the effectiveness of a new multi-slice CT system to study the trabecular bone tissue. The system is capable of acquiring 3D images of 5600×5600×52 voxels on specimens up to 130 mm with a spatial resolution of 22.5 micrometers. This new detector is coupled to a CCD intensified camera (EBCCD) and was patented by the University of Bologna. The CT acquisitions were performed with an experimental setup at Elettra facilities at beamline SYRMEP. The reconstructed images were sections containing the femoral head, femoral neck and trochantere. The used spatial resolution allows to visualize also thin trabeculae, which typically lie in a range below 100 microns. The morphometric trabecular characterization parameters as BV/TV, Tb.Th, Tb.Sp, Tb.N were calculated over three regions of interest. The local variations in trabecular and cortical structure of the examined bone are clearly visible at a level not obtainable with medical CT scanners. The quality of the reconstructed cross sections images confirm that this investigation technique is an advanced tool for high resolution three-dimensional imaging of bone structure.

Original languageEnglish
Pages (from-to)2273-2277
Number of pages5
JournalIEEE Nuclear Science Symposium Conference Record
Publication statusPublished - 2004
Externally publishedYes
Event2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors - Rome, Italy
Duration: 16 Oct 200422 Oct 2004


Dive into the research topics of 'A CCD-based high resolution CT system for analysis of trabecular bone tissue'. Together they form a unique fingerprint.

Cite this