TY - JOUR
T1 - A Core Outcome Set for Trials in CKD
T2 - Report of the Standardized Outcomes in Nephrology–Chronic Kidney Disease (SONG-CKD) Stakeholder Workshops
AU - Matus Gonzalez, Andrea
AU - Cazzolli, Rosanna
AU - Madero, Magdalena
AU - Evangelidis, Nicole
AU - Howell, Martin
AU - Sautenet, Benedicte
AU - Bernier-Jean, Amelie
AU - Cho, Yeoungjee
AU - Sanabria, Laura Cortes
AU - Craig, Jonathan C.
AU - de Boer, Ian H.
AU - Fung, Samuel
AU - Gallego, Daniel
AU - Guha, Chandana
AU - Shen, Jenny I.
AU - Levey, Andrew S.
AU - Levin, Adeera
AU - Lorca, Eduardo
AU - Cabrera, Sebastian
AU - Mellado, Haydee
AU - Molina, Soledad
AU - Atilano, Ximena
AU - Sandino, Lorena
AU - Arancibia, Macarena
AU - Sepulveda, Alejandro
AU - Urra, Marcelo
AU - Bravo, Maria de los Angeles
AU - Manera, Karine
AU - Recabarren, Javier
AU - Okpechi, Ikechi G.
AU - Rossignol, Patrick
AU - Scholes-Robertson, Nicole
AU - Sola, Laura
AU - Teixeira-Pinto, Armando
AU - Usherwood, Tim
AU - Viecelli, Andrea K.
AU - Wheeler, David C.
AU - Widders, Katherine
AU - Jaure, Allison
AU - SONG-CKD Stakeholder Workshop Investigators
PY - 2025/6
Y1 - 2025/6
N2 - Omitting outcomes of importance to patients with chronic kidney disease (CKD) and their caregivers from trials can impede decision making based on patient-centered outcomes. As part of the global Standardized Outcomes in Nephrology–Chronic Kidney Disease (SONG-CKD) initiative, we established a consensus-based set of core outcomes for trials in CKD (prior to the need for kidney replacement therapy). To finalize the proposed set of core outcomes that were identified through focus groups and an international Delphi survey, we convened 2 international stakeholder workshops in English and Spanish languages that involved 61 patients/caregivers and 75 health professionals from 18 countries. Participants were asked to discuss and endorse the potential core outcomes (mortality, kidney function, life participation, and cardiovascular disease), and to provide suggestions for implementing the core outcomes. The discussions were summarized into 4 themes: reflecting a comprehensive approach to health, facilitating patient empowerment in their own care, ensuring applicability to broad geographic areas and populations, and feasibility for implementation. Patients, caregivers, and health professionals agreed that mortality, kidney function, life participation, and cardiovascular disease should be established as core outcomes for trials in CKD.
AB - Omitting outcomes of importance to patients with chronic kidney disease (CKD) and their caregivers from trials can impede decision making based on patient-centered outcomes. As part of the global Standardized Outcomes in Nephrology–Chronic Kidney Disease (SONG-CKD) initiative, we established a consensus-based set of core outcomes for trials in CKD (prior to the need for kidney replacement therapy). To finalize the proposed set of core outcomes that were identified through focus groups and an international Delphi survey, we convened 2 international stakeholder workshops in English and Spanish languages that involved 61 patients/caregivers and 75 health professionals from 18 countries. Participants were asked to discuss and endorse the potential core outcomes (mortality, kidney function, life participation, and cardiovascular disease), and to provide suggestions for implementing the core outcomes. The discussions were summarized into 4 themes: reflecting a comprehensive approach to health, facilitating patient empowerment in their own care, ensuring applicability to broad geographic areas and populations, and feasibility for implementation. Patients, caregivers, and health professionals agreed that mortality, kidney function, life participation, and cardiovascular disease should be established as core outcomes for trials in CKD.
KW - Chronic kidney disease
KW - core outcome set
KW - outcomes
KW - patient-centered care
KW - trials
UR - http://www.scopus.com/inward/record.url?scp=105002745426&partnerID=8YFLogxK
U2 - 10.1053/j.ajkd.2024.10.013
DO - 10.1053/j.ajkd.2024.10.013
M3 - Article
C2 - 39855535
AN - SCOPUS:105002745426
SN - 0272-6386
VL - 85
SP - 745
EP - 753
JO - American Journal of Kidney Diseases
JF - American Journal of Kidney Diseases
IS - 6
ER -
