A Green One-Pot Protocol for Regioselective Synthesis of New Substituted 7,8-Dihydrocinnoline-5(6H)-ones

Jabbar Khalafy, Mehdi Rimaz, Mahnaz Ezzati, Rolf Prager

    Research output: Contribution to journalArticle

    18 Citations (Scopus)

    Abstract

    A simple regioselective synthesis of cinnoline derivatives was achieved by a one-pot three component synthetic methodology. New substituted 7,8-dihydrocinnolin-5(6H)-ones are prepared via one-pot three component reaction of arylglyoxals with 1,3-cyclohexanedione and dimedone in the presence of hydrazine hydrate in moderate to good yields.

    Original languageEnglish
    Pages (from-to)2890-2896
    Number of pages7
    JournalBulletin of the Korean Chemical Society
    Volume33
    Issue number9
    DOIs
    Publication statusPublished - 20 Sep 2012

    Keywords

    • 1,3-Cyclohexanedione
    • Arylglyoxal
    • Cinnoline
    • Dimedone
    • Regioselective

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