A guide to missing data for the pediatric nephrologist

Nicholas G. Larkins, Jonathan C. Craig, Armando Teixeira-Pinto

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Missing data is an important and common source of bias in clinical research. Readers should be alert to and consider the impact of missing data when reading studies. Beyond preventing missing data in the first place, through good study design and conduct, there are different strategies available to handle data containing missing observations. Complete case analysis is often biased unless data are missing completely at random. Better methods of handling missing data include multiple imputation and models using likelihood-based estimation. With advancing computing power and modern statistical software, these methods are within the reach of clinician-researchers under guidance of a biostatistician. As clinicians reading papers, we need to continue to update our understanding of statistical methods, so that we understand the limitations of these techniques and can critically interpret literature.

Original languageEnglish
Pages (from-to)223-231
Number of pages9
JournalPEDIATRIC NEPHROLOGY
Volume34
Issue number2
DOIs
Publication statusPublished - 1 Feb 2019
Externally publishedYes

Keywords

  • Epidemiology
  • Multiple imputation
  • Nephrology
  • Statistics

Fingerprint Dive into the research topics of 'A guide to missing data for the pediatric nephrologist'. Together they form a unique fingerprint.

Cite this