A meta-analysis of sperm donation offspring health outcomes

Damian Adams; Robyn Clark; Michael Davies; Sheryl de Lacey

doi:10.1017/S2040174416000489

A meta-analysis of sperm donation offspring health outcomes

Damian Adams, Robyn Clark, Michael Davies, Sheryl de Lacey

Research output: Contribution to journal › Review article › peer-review

16 Citations (Scopus)

Abstract

Although the use of donor sperm as a treatment modality for male infertility has become common place, the health outcomes for those conceived has been poorly studied. A structured search of the literature using PubMed, EMBASE and Cochrane Reviews was performed to investigate the health outcomes of offspring conceived from donor sperm. Eight studies were eligible and included in the review, and of these, three were included in a meta-analysis. Meta-analysis of clinical outcomes showed that donor sperm neonates are not at increased risk of being born of low birth weight (<2500 g), preterm (<37 weeks) or with increased incidences of birth defects, than spontaneously conceived neonates.

Original language	English
Pages (from-to)	44-55
Number of pages	12
Journal	Journal of Developmental Origins of Health and Disease
Volume	8
Issue number	1
DOIs	https://doi.org/10.1017/S2040174416000489
Publication status	Published - 1 Feb 2017

Keywords

Donor conception
meta-analysis
neonate
outcome
sperm

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10.1017/S2040174416000489

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A meta-analysis of sperm donation offspring health outcomes

Abstract

Keywords

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