A neutrophilic dermatosis following treatment of myelofibrosis with ruxolitinib: An emerging phenomenon?

Melinda Jiang, Alain Khoi Tran, Gillian Marshman

Research output: Contribution to journalLetterpeer-review

2 Citations (Scopus)

Abstract

Ruxolitinib is a Janus kinase (JAK) inhibitor used in the treatment of myelofibrosis. In the last six years, there have been four cases of Sweet syndrome (SS) reported in patients with ruxolitinib-treated myelofibrosis. (1-4) To our knowledge, this is the first case reported on a ruxolitinib-associated neutrophilic dermatosis presenting with a pathergy phenomenon at a post-operative wound site, accompanied by mucosal involvement.
Original languageEnglish
Pages (from-to)e607-e609
Number of pages3
JournalAustralasian Journal of Dermatology
Volume62
Issue number4
DOIs
Publication statusPublished - Nov 2021

Keywords

  • neutrophilic dermatosis
  • pathergy
  • pyoderma gangrenosum
  • ruxolitinib
  • sweet syndrome
  • tyrosine kinase inhibitor

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