Rheumatoid arthritis (RA) is a chronic destructive inflammatory disease of the joints. The collagen antibody-induced arthritis (CAIA) mouse model provides a straightforward and rapid means of producing pathologies associated with inflammatory arthritis. However, regardless of the rodent model used to study the disease, current non-invasive read outs of disease severity, such as paw thickness/volume or clinical score grades, rely on assessment of edema, rather than on the underlying synovial proliferation, inflammatory cell infiltration, and osteoclastic bone resorption. To quantify the bone erosion in murine models of inflammatory arthritis, recent studies utilise micro-computed tomography (micro-CT).
|Number of pages||1|
|Publication status||Published - 2013|
|Event||Australian & New Zealand Orthopaedic Research Society, 19th Annual Scientific Meeting - Sydney, Australia|
Duration: 4 Sep 2013 → …
|Conference||Australian & New Zealand Orthopaedic Research Society, 19th Annual Scientific Meeting|
|Period||4/09/13 → …|