A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding

Carlo Iavarone, Katrin Ramsauer, Andriy V. Kubarenko, Jason C. Debasitis, Igor Leykin, Alexander N.R. Weber, Owen M. Siggs, Bruce Beutler, Pu Zhang, Gillis Otten, Ugo D'Oro, Nicholas M. Valiante, M. Lamine Mbow, Alberto Visintin

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24 Citations (Scopus)

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Biochemistry, Genetics and Molecular Biology

Immunology and Microbiology