A rare presentation of gastric signet ring cells: Signet ring cell lymphoma

Sithara Venkateshwar; Thomas Alexander; Moses Ambroise; Renu G’boy Varghese; Anita Ramdas

doi:10.7860/JCDR/2014/10811.5323

A rare presentation of gastric signet ring cells: Signet ring cell lymphoma

Sithara Venkateshwar
, Thomas Alexander
, Moses Ambroise
, Renu G’boy Varghese
, Anita Ramdas

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We herewith present a rare and interesting case of gastric signet ring cell lymphoma (SRCL) in a 40-year-old retroviral positive lady. SRCL is a rare morphological variant of nodal lymphomas.Biopsy from the suspected lesion in the stomach showed diffuse sheets of cells with a large central vacuole displacing the nucleus to the periphery of the cell, imparting signet ring cell morphology. Negative reaction to PAS (Periodic acid Schiff) stain and subsequent strong positivity for the immunohistochemical markers such as CD45 (Leucocyte commonantigen) and CD20, a B-cell marker helped us to arrive at a diagnosis of signet ring B- cell lymphoma.

Original language	English
Pages (from-to)	FD05-FD06
Journal	Journal of Clinical and Diagnostic Research
Volume	8
Issue number	12
DOIs	https://doi.org/10.7860/JCDR/2014/10811.5323
Publication status	Published - 5 Dec 2014
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Signet ring cell lymphoma

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10.7860/JCDR/2014/10811.5323Licence: CC BY-NC-ND

Final published versionFinal published version, 1.08 MBLicence: CC BY-NC-ND

Cite this

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title = "A rare presentation of gastric signet ring cells: Signet ring cell lymphoma",

abstract = "We herewith present a rare and interesting case of gastric signet ring cell lymphoma (SRCL) in a 40-year-old retroviral positive lady. SRCL is a rare morphological variant of nodal lymphomas.Biopsy from the suspected lesion in the stomach showed diffuse sheets of cells with a large central vacuole displacing the nucleus to the periphery of the cell, imparting signet ring cell morphology. Negative reaction to PAS (Periodic acid Schiff) stain and subsequent strong positivity for the immunohistochemical markers such as CD45 (Leucocyte commonantigen) and CD20, a B-cell marker helped us to arrive at a diagnosis of signet ring B- cell lymphoma.",

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T1 - A rare presentation of gastric signet ring cells

T2 - Signet ring cell lymphoma

AU - Venkateshwar, Sithara

AU - Alexander, Thomas

AU - Ambroise, Moses

AU - Varghese, Renu G’boy

AU - Ramdas, Anita

PY - 2014/12/5

Y1 - 2014/12/5

N2 - We herewith present a rare and interesting case of gastric signet ring cell lymphoma (SRCL) in a 40-year-old retroviral positive lady. SRCL is a rare morphological variant of nodal lymphomas.Biopsy from the suspected lesion in the stomach showed diffuse sheets of cells with a large central vacuole displacing the nucleus to the periphery of the cell, imparting signet ring cell morphology. Negative reaction to PAS (Periodic acid Schiff) stain and subsequent strong positivity for the immunohistochemical markers such as CD45 (Leucocyte commonantigen) and CD20, a B-cell marker helped us to arrive at a diagnosis of signet ring B- cell lymphoma.

AB - We herewith present a rare and interesting case of gastric signet ring cell lymphoma (SRCL) in a 40-year-old retroviral positive lady. SRCL is a rare morphological variant of nodal lymphomas.Biopsy from the suspected lesion in the stomach showed diffuse sheets of cells with a large central vacuole displacing the nucleus to the periphery of the cell, imparting signet ring cell morphology. Negative reaction to PAS (Periodic acid Schiff) stain and subsequent strong positivity for the immunohistochemical markers such as CD45 (Leucocyte commonantigen) and CD20, a B-cell marker helped us to arrive at a diagnosis of signet ring B- cell lymphoma.

KW - Signet ring cell lymphoma

UR - https://www.scopus.com/pages/publications/84919345201

U2 - 10.7860/JCDR/2014/10811.5323

DO - 10.7860/JCDR/2014/10811.5323

M3 - Article

AN - SCOPUS:84919345201

SN - 2249-782X

VL - 8

SP - FD05-FD06

JO - Journal of Clinical and Diagnostic Research

JF - Journal of Clinical and Diagnostic Research

IS - 12

ER -

A rare presentation of gastric signet ring cells: Signet ring cell lymphoma

Abstract

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Keywords

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