TY - JOUR
T1 - A Simple One-Pot, Three Component Synthesis of 3-Arylpyrimido[4,5-c]pyridazine-5,7(6H,8H)-diones and their Sulfur Analogues as Potential Monoamine Oxidase Inhibitors
AU - Rimaz, Mehdi
AU - Khalafy, Jabbar
AU - Pesyan, Nader
AU - Prager, Rolf
PY - 2010
Y1 - 2010
N2 - Several new 3-arylpyrimido[4,5-c]pyridazine-5,7(6H,8H)-diones and 3-aryl-5-oxo-7-thioxo-7,8-dihydropyrimido[4,5-c]pyridazin-5(6H)-ones have been synthesized by a three-component reaction of barbituric acid or thiobarbituric acid with arylglyoxals in the presence of a catalytic amount of pyridine and hydrazine hydrate at room temperature in water.
AB - Several new 3-arylpyrimido[4,5-c]pyridazine-5,7(6H,8H)-diones and 3-aryl-5-oxo-7-thioxo-7,8-dihydropyrimido[4,5-c]pyridazin-5(6H)-ones have been synthesized by a three-component reaction of barbituric acid or thiobarbituric acid with arylglyoxals in the presence of a catalytic amount of pyridine and hydrazine hydrate at room temperature in water.
UR - http://www.scopus.com/inward/record.url?scp=77950275420&partnerID=8YFLogxK
U2 - 10.1071/CH09569
DO - 10.1071/CH09569
M3 - Article
SN - 0004-9425
VL - 63
SP - 507
EP - 510
JO - Australian Journal of Chemistry
JF - Australian Journal of Chemistry
IS - 3
ER -