Adequacy of published screening criteria for retinopathy of prematurity

Deepa Taranath, Dickson Oh, Miriam Keane, Helen Fabel, Peter Marshall

    Research output: Contribution to journalArticle

    Abstract

    Background: Criteria for screening preterm infants for retinopathy of prematurity vary around the world. We aimed to analyse the efficacy of alternative screening criteria. Design: We collected retrospective data at a tertiary level neonatal nursery. Participants: Our participants were 1007 babies, born between 1997 and 2011, at <32weeks gestational age or <1500g birth weight (as recommended by the National Health and Medical Research Council in 1996), who had completed follow-up to full retinal vascularization, with defined presence or absence of retinopathy of prematurity. Methods: We determined whether disease would be detected using an alternative Australian screening model (gestational age <30weeks or birth weight <1250g) or screening criteria utilized in developed countries with similar standards of neonatal care. Main Outcome Measures: Detection of retinopathy of prematurity is our main outcome. Results: Using several of the alternative criteria, two neonates with clinically significant retinopathy of prematurity, one of whom required laser treatment to preserve sight, would not have been screened, and their disease may have gone undetected. Use of <30weeks gestational age or <1500g birth weight as the criteria would still have screened these infants but would have reduced the number of infants screened by 24.9%. Conclusions: Some commonly utilized international screening criteria for retinopathy of prematurity may risk clinically significant cases being missed and others may screen babies unnecessarily. Alternative criteria should be considered and '<30weeks gestational age and/or <1500g birth weight' appears a viable option.

    Original languageEnglish
    Pages (from-to)121-127
    Number of pages7
    JournalClinical and Experimental Ophthalmology
    Volume44
    Issue number2
    DOIs
    Publication statusPublished - 1 Mar 2016

    Keywords

    • Baby
    • Birth weight
    • Gestational age
    • Retinopathy of prematurity
    • Screening

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