Adrenaline overdose in pediatric anaphylaxis: a case report

Pui Yi Lily Liew; John Andrew Craven

doi:10.1186/s13256-017-1290-7

Adrenaline overdose in pediatric anaphylaxis: a case report

Pui Yi Lily Liew
, John Andrew Craven

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

114 Downloads (Pure)

Abstract

Background: Adrenaline is the standard treatment for anaphylaxis but appropriate administration remains challenging, and iatrogenic overdose is easily overlooked. Despite the established importance of pediatric blood pressure measurement, its use remains inconsistent in clinical practice. Case presentation: We report a case of adrenaline overdose in a 9-year-old white boy with anaphylaxis, where signs of adrenaline overdose were indistinguishable from progressive shock until blood pressure measurement was taken. Conclusions: The consequences of under-dosing adrenaline in anaphylaxis are well-recognized, but the converse is less so. Blood pressure measurement should be a routine part of pediatric assessment as it is key to differentiating adrenaline overdose from anaphylactic shock.

Original language	English
Article number	129
Number of pages	3
Journal	Journal of Medical Case Reports
Volume	11
Issue number	1
DOIs	https://doi.org/10.1186/s13256-017-1290-7
Publication status	Published - 8 May 2017
Externally published	Yes

Keywords

Adrenaline
Anaphylaxis
Blood pressure
Case report
Children
Epinephrine
Overdose
Pediatric

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10.1186/s13256-017-1290-7Licence: CC BY

Liew_Adrenaline_P2017Final published version, 346 KBLicence: CC BY

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title = "Adrenaline overdose in pediatric anaphylaxis: a case report",

abstract = "Background: Adrenaline is the standard treatment for anaphylaxis but appropriate administration remains challenging, and iatrogenic overdose is easily overlooked. Despite the established importance of pediatric blood pressure measurement, its use remains inconsistent in clinical practice. Case presentation: We report a case of adrenaline overdose in a 9-year-old white boy with anaphylaxis, where signs of adrenaline overdose were indistinguishable from progressive shock until blood pressure measurement was taken. Conclusions: The consequences of under-dosing adrenaline in anaphylaxis are well-recognized, but the converse is less so. Blood pressure measurement should be a routine part of pediatric assessment as it is key to differentiating adrenaline overdose from anaphylactic shock.",

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AU - Craven, John Andrew

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N2 - Background: Adrenaline is the standard treatment for anaphylaxis but appropriate administration remains challenging, and iatrogenic overdose is easily overlooked. Despite the established importance of pediatric blood pressure measurement, its use remains inconsistent in clinical practice. Case presentation: We report a case of adrenaline overdose in a 9-year-old white boy with anaphylaxis, where signs of adrenaline overdose were indistinguishable from progressive shock until blood pressure measurement was taken. Conclusions: The consequences of under-dosing adrenaline in anaphylaxis are well-recognized, but the converse is less so. Blood pressure measurement should be a routine part of pediatric assessment as it is key to differentiating adrenaline overdose from anaphylactic shock.

AB - Background: Adrenaline is the standard treatment for anaphylaxis but appropriate administration remains challenging, and iatrogenic overdose is easily overlooked. Despite the established importance of pediatric blood pressure measurement, its use remains inconsistent in clinical practice. Case presentation: We report a case of adrenaline overdose in a 9-year-old white boy with anaphylaxis, where signs of adrenaline overdose were indistinguishable from progressive shock until blood pressure measurement was taken. Conclusions: The consequences of under-dosing adrenaline in anaphylaxis are well-recognized, but the converse is less so. Blood pressure measurement should be a routine part of pediatric assessment as it is key to differentiating adrenaline overdose from anaphylactic shock.

KW - Adrenaline

KW - Anaphylaxis

KW - Blood pressure

KW - Case report

KW - Children

KW - Epinephrine

KW - Overdose

KW - Pediatric

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SN - 1752-1947

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ER -

Adrenaline overdose in pediatric anaphylaxis: a case report

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Adrenaline overdose in pediatric anaphylaxis: a case report

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