Advances of Melatonin-Based Therapies in the Treatment of Disturbed Sleep and Mood

Megan Alston, Sean W Cain, Shantha M W Rajaratnam

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

13 Citations (Scopus)

Abstract

Melatonin and melatonin agonists offer novel treatments for sleep and mood disorders, particularly where circadian misalignment is also present. The therapies offer both phase-shifting and sleep-promoting effects and have shown potential to treat advanced and delayed sleep-wake phase disorder, non-24-h sleep-wake cycle, jetlag, shift work disorder, insomnia, seasonal affective disorder and major depressive disorder.

Original languageEnglish
Title of host publicationSleep-Wake Neurobiology and Pharmacology
EditorsHans-Peter Landolt, Derk-Jan Dijk
Place of PublicationSwitzerland
PublisherSpringer Nature
Pages305-319
Number of pages15
ISBN (Electronic)978-3-030-11272-1
ISBN (Print)978-3-030-11270-7
DOIs
Publication statusPublished - 2019
Externally publishedYes

Publication series

NameHandbook of Experimental Pharmacology
Volume253
ISSN (Print)0171-2004
ISSN (Electronic)1865-0325

Keywords

  • Agomelatine
  • Circadian rhythm
  • Circadin
  • Major depressive disorder
  • Melatonin
  • Melatonin agonist
  • Mood
  • Ramelteon
  • Sleep
  • Tasimelteon

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