Advocating for both Environmental and Clinical Approaches to Control Human Strongyloidiasis

Meruyert Beknazarova, Harriet Whiley, Kirstin Ross

    Research output: Contribution to journalReview article

    7 Citations (Scopus)

    Abstract

    Strongyloidiasis is an underestimated disease caused by the soil-transmitted parasite of the genus Strongyloides. It is prevalent in socioeconomically disadvantaged communities and it is estimated that global infection could be as high as 370 million people. This paper explores current methods of strongyloidiasis treatment, which rely on administration of anthelminthic drugs. However these drugs cannot prevent reinfection and drug resistance has already been observed in veterinary models. This highlights the need for a combined approach for controlling Strongyloides that includes both clinical treatment and environmental control methods. Currently, nematicides are widely used to control plant parasites. The review suggests that due to the species’ similarity and similar modes of action, these nematicides could also be used to control animal and human parasitic nematodes in the environment.

    Original languageEnglish
    Article number59
    Pages (from-to)aRT: 59
    Number of pages10
    JournalPathogens
    Volume5
    Issue number4
    DOIs
    Publication statusPublished - Dec 2016

    Keywords

    • Anthelminthic drugs
    • Ivermectin
    • Nematicides
    • Resistance
    • Strongyloides stercoralis
    • Strongyloidiasis

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