Age and gender variations in the management of ischaemic stroke in China

Yining Huang, Ji-Guang Wang, Jade Wei, Alexander Headley, Lawrence Wong, Emma Heeley, Hisatomi Arima, Jian Sun, Qiang Li, Ming Liu, Zhengyi Li, Li'e Wu, Yan Cheng, Qifang Huang, Shi-Hong Zhang, En Xu, Qidong Yang, Chuanzhen Lu, Craig Anderson

    Research output: Contribution to journalArticlepeer-review

    32 Citations (Scopus)


    Background: Stroke is a major health issue in China. Aims: We aimed to describe the management of patients admitted to hospitals in China with acute ischaemic stroke, and to determine whether there were any differences by age and gender. Methods: Using a multicentre prospective hospital register across all eight major economic (geographic) regions in China, data on the socioeconomic characteristics, medical history, clinical features, and in-hospital investigations, management, and outcomes were collected on consecutive patients with acute stroke due to cerebral ischaemia during a 5-month period in 2006. Results: Overall, traditional Chinese medicine and neuroprotectant use were remarkably high, with nearly 80% of patients receiving the former and >70% receiving the latter in hospital. Length of hospital stay was also long (median duration 16-days). Multivariate analyses revealed no clinically important differences in management between the genders. For the age-specific analyses, there were significant trends of decreasing use of thrombolysis (P=0·04), warfarin (P=0·01), corticosteroids (P=0·03), and lipid-lowering therapy (P=0·001); however, more assisted feeding (P=0·004) and rising rates of disability and in-hospital complications occurred with increasing age. Conclusions: New information is provided regarding the current state of ischaemic stroke management in China. Notably, there is high use of traditional Chinese medicine and neuroprotectants and long lengths of hospital stay. Similar to many other countries, differences in stroke care and management by age and gender also exist to a small extent in China.

    Original languageEnglish
    Pages (from-to)351-359
    Number of pages9
    JournalInternational Journal of Stroke
    Issue number5
    Publication statusPublished - Oct 2010


    • Acute
    • Age
    • China
    • Clinical practice
    • Gender
    • Management
    • Stroke


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