Age-related variations in human lymphocyte DNA

D. R. Turner, A. A. Morley, R. S. Seshadri, Judith R. Sorrell

    Research output: Contribution to journalArticlepeer-review

    17 Citations (Scopus)


    The molecular weigth of DNA from human peripheral lymphocytes has been measured on alkaline sucrose density gradients. The number average molecular weight (MN) of DNA is found to decrease as the age of the donor increases. This result is discussed with reference to lesions in DNA, both repairable and non-repairable, which may accumulate with age.

    Original languageEnglish
    Pages (from-to)305-309
    Number of pages5
    JournalMechanisms of Ageing and Development
    Issue number3
    Publication statusPublished - Nov 1981


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