Age-specific prevalence of herpes simplex viruses in Melbourne.

James Knox; Craig Redden; Bernard Walton; Robert Baird

doi:10.1097/PAT.0b013e328340e4f6

Age-specific prevalence of herpes simplex viruses in Melbourne.

James Knox, Craig Redden, Bernard Walton, Robert Baird

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Aims: To characterise the epidemiology of anogenital herpes in Melbourne by detailing the age-specific prevalence of herpes simplex virus (HSV) 1 and HSV 2. Methods: A cross-sectional study of 2055 anogenital specimens assayed by polymerase chain reaction (PCR) for HSV 1 and 2 at Melbourne Pathology from 1 August 2004 to 11 May 2005 was conducted. Results were analysed by age and sex. Results: PCR demonstrated HSV 1 in 44.1% of all anogenital herpes cases. The relative prevalence of HSV 1 decreased as a function of increasing age. In patients under the age of 20, 18.2% of cases of anogenital herpes were due to HSV 2, as compared with 84.6% in patients over the age of 50. Conclusions: In this study population a clear relationship is seen between age and relative frequency of HSV 1 and 2 as a cause of anogenital herpes. HSV 2 accounts for only a small proportion of infections in younger patients.

Original language	English
Pages (from-to)	64-66
Number of pages	3
Journal	Pathology
Volume	43
Issue number	1
DOIs	https://doi.org/10.1097/PAT.0b013e328340e4f6
Publication status	Published - Jan 2011

Keywords

Epidemiology
Herpes genitalis
Herpes simplex
Herpesviridae infections
Polymerase chain reaction
Prevalence

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10.1097/PAT.0b013e328340e4f6

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title = "Age-specific prevalence of herpes simplex viruses in Melbourne.",

abstract = "Aims: To characterise the epidemiology of anogenital herpes in Melbourne by detailing the age-specific prevalence of herpes simplex virus (HSV) 1 and HSV 2. Methods: A cross-sectional study of 2055 anogenital specimens assayed by polymerase chain reaction (PCR) for HSV 1 and 2 at Melbourne Pathology from 1 August 2004 to 11 May 2005 was conducted. Results were analysed by age and sex. Results: PCR demonstrated HSV 1 in 44.1% of all anogenital herpes cases. The relative prevalence of HSV 1 decreased as a function of increasing age. In patients under the age of 20, 18.2% of cases of anogenital herpes were due to HSV 2, as compared with 84.6% in patients over the age of 50. Conclusions: In this study population a clear relationship is seen between age and relative frequency of HSV 1 and 2 as a cause of anogenital herpes. HSV 2 accounts for only a small proportion of infections in younger patients.",

keywords = "Epidemiology, Herpes genitalis, Herpes simplex, Herpesviridae infections, Polymerase chain reaction, Prevalence",

author = "James Knox and Craig Redden and Bernard Walton and Robert Baird",

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T1 - Age-specific prevalence of herpes simplex viruses in Melbourne.

AU - Knox, James

AU - Redden, Craig

AU - Walton, Bernard

AU - Baird, Robert

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N2 - Aims: To characterise the epidemiology of anogenital herpes in Melbourne by detailing the age-specific prevalence of herpes simplex virus (HSV) 1 and HSV 2. Methods: A cross-sectional study of 2055 anogenital specimens assayed by polymerase chain reaction (PCR) for HSV 1 and 2 at Melbourne Pathology from 1 August 2004 to 11 May 2005 was conducted. Results were analysed by age and sex. Results: PCR demonstrated HSV 1 in 44.1% of all anogenital herpes cases. The relative prevalence of HSV 1 decreased as a function of increasing age. In patients under the age of 20, 18.2% of cases of anogenital herpes were due to HSV 2, as compared with 84.6% in patients over the age of 50. Conclusions: In this study population a clear relationship is seen between age and relative frequency of HSV 1 and 2 as a cause of anogenital herpes. HSV 2 accounts for only a small proportion of infections in younger patients.

AB - Aims: To characterise the epidemiology of anogenital herpes in Melbourne by detailing the age-specific prevalence of herpes simplex virus (HSV) 1 and HSV 2. Methods: A cross-sectional study of 2055 anogenital specimens assayed by polymerase chain reaction (PCR) for HSV 1 and 2 at Melbourne Pathology from 1 August 2004 to 11 May 2005 was conducted. Results were analysed by age and sex. Results: PCR demonstrated HSV 1 in 44.1% of all anogenital herpes cases. The relative prevalence of HSV 1 decreased as a function of increasing age. In patients under the age of 20, 18.2% of cases of anogenital herpes were due to HSV 2, as compared with 84.6% in patients over the age of 50. Conclusions: In this study population a clear relationship is seen between age and relative frequency of HSV 1 and 2 as a cause of anogenital herpes. HSV 2 accounts for only a small proportion of infections in younger patients.

KW - Epidemiology

KW - Herpes genitalis

KW - Herpes simplex

KW - Herpesviridae infections

KW - Polymerase chain reaction

KW - Prevalence

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Age-specific prevalence of herpes simplex viruses in Melbourne.

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Keywords

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