Aggregation-­Induced Emission Bioprobe for Protein Detection and Imaging to Screen the Human Diseases

Sanaz Naghibi, Youhong Tang

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Proteins are the essential biomacromolecules in the body with different functions, from providing the structure of cells to catalyzing biochemical reactions, to transferring goods or messages inside the biological systems. As the actual executors of genes and genetic information, proteins have an important role in biological processes. According to the literature, they are too sensitive to physical and chemical degradation processes. Therefore, qualification, quantification, and characterization of proteins could be considered as biomarkers for disease onset and progression diagnosis. Up to now, there has been extended a wide variety of trajectories to understand the functions of proteins brought about brilliant approaches in the protein-related diseases arena. This chapter has been dedicated to the emanating of aggregation-induced emission luminogens in protein detection and identification for biomedical applications.

Original languageEnglish
Title of host publicationOrganic and Inorganic Materials Based Sensors
EditorsSangita Das, Sabu Thomas, Partha Pratim Das
Place of PublicationWeinheim, Germany
PublisherWiley
Chapter19
Pages401-419
Number of pages19
Volume1
ISBN (Electronic)978-3-527-83426-6, 978-3-527-84667-2, 978-3-527-84668-9
ISBN (Print)978-3-527-35244-9
DOIs
Publication statusPublished - 2024

Keywords

  • AIE luminogens
  • Confocal microscopy
  • Fluorescence imaging
  • Real-time protein imaging
  • Theranostic imaging

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