Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures

J. A. Kanis, N. C. Harvey, E. McCloskey, O. Bruyère, N. Veronese, M. Lorentzon, C. Cooper, R. Rizzoli, G. Adib, N. Al-Daghri, C. Campusano, M. Chandran, B. Dawson-Hughes, K. Javaid, F. Jiwa, H. Johansson, J. K. Lee, E. Liu, D. Messina, O. MkinsiD. Pinto, D. Prieto-Alhambra, K. Saag, W. Xia, L. Zakraoui, J. Y. Reginster

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19 Citations (Scopus)

Abstract

Summary: Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures. Introduction: The International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2019. This manuscript seeks to apply this in an international setting, taking additional account of further categorisation of increased risk of fracture, which may inform choice of therapeutic approach. Methods: Clinical perspective and updated literature search. Results: The following areas are reviewed: categorisation of fracture risk and general pharmacological management of osteoporosis. Conclusions: A platform is provided on which specific guidelines can be developed for national use to characterise fracture risk and direct interventions.

Original languageEnglish
Pages (from-to)1-12
Number of pages12
JournalOsteoporosis International
Volume31
Issue number1
DOIs
Publication statusPublished - 1 Jan 2020
Externally publishedYes

Bibliographical note

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

Keywords

  • Anabolic agents
  • Fracture risk assessment
  • FRAX
  • Inhibitors of bone resorption
  • Treatment of osteoporosis

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    Kanis, J. A., Harvey, N. C., McCloskey, E., Bruyère, O., Veronese, N., Lorentzon, M., Cooper, C., Rizzoli, R., Adib, G., Al-Daghri, N., Campusano, C., Chandran, M., Dawson-Hughes, B., Javaid, K., Jiwa, F., Johansson, H., Lee, J. K., Liu, E., Messina, D., ... Reginster, J. Y. (2020). Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures. Osteoporosis International, 31(1), 1-12. https://doi.org/10.1007/s00198-019-05176-3